A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.24.71
| Accepted Name |
|---|
| Endothelin-converting enzyme 1.
|
| Alternative Name(s) |
|---|
| ECE-1. |
| Reaction catalysed |
|---|
| Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1 |
| Cofactor(s) |
|---|
| Zn(2+).
|
| Comment(s) |
|---|
- Phosphoramidon-sensitive.
- Belongs to peptidase family M13.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.71 |
| EC2PDB | 3.4.24.71 |
| ExplorEnz | 3.4.24.71 |
| PRIAM enzyme-specific profiles | 3.4.24.71 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.71 |
| IUBMB Enzyme Nomenclature | 3.4.24.71 |
| IntEnz | 3.4.24.71 |
| MEDLINE | Find literature relating to 3.4.24.71 |
| MetaCyc | 3.4.24.71 |
| UniProtKB/Swiss-Prot |
| P42891, ECE1_BOVIN; | P97739, ECE1_CAVPO; | P42892, ECE1_HUMAN; |
| Q4PZA2, ECE1_MOUSE; | P42893, ECE1_RAT; | F1N476, ECE2_BOVIN; |
| P0DPD6, ECE2_HUMAN; | B2RQR8, ECE2_MOUSE; | P0DPE2, EFCE2_BOVIN; |
| P0DPD8, EFCE2_HUMAN; | P0DPD9, EFCE2_MOUSE; |
|
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