ENZYME entry: EC 3.4.24.80
| Accepted Name | ||||||||
|---|---|---|---|---|---|---|---|---|
| membrane-type matrix metalloproteinase-1 | ||||||||
| Alternative Name(s) | ||||||||
| matrix metalloproteinase 14 | ||||||||
| Reaction catalysed | ||||||||
| Endopeptidase activity. Activates progelatinase A by cleavage of the propeptide at 37-Asn-|-Leu-38. Other bonds hydrolyzed include 35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-342, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan interglobular domain | ||||||||
| Comment(s) | ||||||||
| ||||||||
| Cross-references | ||||||||
| BRENDA | 3.4.24.80 | |||||||
| EC2PDB | 3.4.24.80 | |||||||
| ExplorEnz | 3.4.24.80 | |||||||
| PRIAM enzyme-specific profiles | 3.4.24.80 | |||||||
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.80 | |||||||
| IUBMB Enzyme Nomenclature | 3.4.24.80 | |||||||
| IntEnz | 3.4.24.80 | |||||||
| MEDLINE | Find literature relating to 3.4.24.80 | |||||||
| MetaCyc | 3.4.24.80 | |||||||
| Rhea expert-curated reactions | 3.4.24.80 | |||||||
| UniProtKB/Swiss-Prot |
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