ID 3.4.24.81 DE ADAM10 endopeptidase. AN Kuzbanian protein. AN myelin-associated disintegrin metalloproteinase. CA Endopeptidase of broad specificity. CC -!- Partially responsible for the 'alpha-secretase' activity in brain CC that degrades the potentially harmful beta-amyloid peptide. CC -!- Work with ADAM10-deficient mice supports a role in Notch signaling. CC -!- Belongs to peptidase family M12. DR Q10741, ADA10_BOVIN; G5EFD9, ADA10_CAEEL; O14672, ADA10_HUMAN; DR O35598, ADA10_MOUSE; O77633, ADA10_PIG ; Q10743, ADA10_RAT ; DR Q8JIY1, ADA10_XENLA; //