ID 3.4.24.82 DE ADAMTS-4 endopeptidase. AN aggrecanase-1. CA Glutamyl endopeptidase. Bonds cleaved include 370-Thr-Glu-Gly-Glu-|-Ala- CA Arg-Gly-Ser-377 in the interglobular domain of mammalian aggrecan. CC -!- Thought to be biologically significant for the degradation of the CC aggrecan component of cartilage matrix. CC -!- Belongs to peptidase family M12. DR Q9TT93, ATS4_BOVIN ; O75173, ATS4_HUMAN ; Q8BNJ2, ATS4_MOUSE ; DR Q5RFQ8, ATS4_PONAB ; Q9ESP7, ATS4_RAT ; //