ENZYME entry: EC 3.4.24.84
Accepted Name |
Ste24 endopeptidase.
|
Alternative Name(s) |
CAAX prenyl protease 1. |
prenyl protein-specific endoprotease 1. |
Reaction catalysed |
The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids |
Comment(s) |
- One of two enzymes that can catalyze this processing step for mating
a-factor in Saccharomyces cerevisiae.
- Subsequently, the S-isoprenylated cysteine residue that forms the new
C-terminus is methyl-esterified and forms a hydrophobic membrane-
anchor.
- Belongs to peptidase family M48.
|
Cross-references |
BRENDA | 3.4.24.84 |
EC2PDB | 3.4.24.84 |
ExplorEnz | 3.4.24.84 |
PRIAM enzyme-specific profiles | 3.4.24.84 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.84 |
IUBMB Enzyme Nomenclature | 3.4.24.84 |
IntEnz | 3.4.24.84 |
MEDLINE | Find literature relating to 3.4.24.84 |
MetaCyc | 3.4.24.84 |
Rhea expert-curated reactions | 3.4.24.84 |
UniProtKB/Swiss-Prot |
|
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