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ENZYME

ENZYME entry: EC 3.5.1.104

PURL: https://purl.expasy.org/enzyme/EC/3.5.1.104
Accepted Name
peptidoglycan-N-acetylglucosamine deacetylase
Alternative Name(s)
N-acetylglucosamine deacetylase
peptidoglycan deacetylase
peptidoglycan GlcNAc deacetylase
peptidoglycan N-acetylglucosamine deacetylase
Reaction catalysed
peptidoglycan-N-acetyl-D-glucosamine + H2O = peptidoglycan-D-glucosamine + acetate
Comment(s)
  • Modification of peptidoglycan by N-deacetylation is an important factor in virulence of Helicobacter pylori, Listeria monocytogenes and Streptococcus suis.
  • The enzyme from Streptococcus pneumoniae is a metalloenzyme using a His-His-Asp zinc-binding triad with a nearby aspartic acid and histidine acting as the catalytic base and acid, respectively.
Cross-references
BRENDA3.5.1.104
EC2PDB3.5.1.104
ExplorEnz3.5.1.104
KEGG Ligand Database for Enzyme Nomenclature3.5.1.104
IUBMB Enzyme Nomenclature3.5.1.104
MEDLINEFind literature relating to 3.5.1.104
MetaCyc3.5.1.104
Rhea expert-curated reactions3.5.1.104
UniProtKB/Swiss-Prot
Q81EK9, PGDA1_BACCRQ81EJ6, PGDA2_BACCRQ81AF4, PGDA3_BACCR
D4B5F9, PGDA_ARTBCA0A0H3GDH9, PGDA_LISM4A0A3Q0NBH7, PGDA_LISMG
Q8Y9V5, PGDA_LISMOQ8DP63, PGDA_STRR6

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-