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ENZYME

ENZYME entry: EC 3.5.1.109

PURL: https://purl.expasy.org/enzyme/EC/3.5.1.109
Accepted Name
sphingomyelin deacylase
Alternative Name(s)
glucosylceramide sphingomyelin deacylase
SM deacylase
SMGCer deacylase
SM glucosylceramide GCer deacylase
sphingomyelin glucosylceramide deacylase
Reaction catalysed
  • a sphingomyelin + H2O = sphing-4-enine-phosphocholine + a carboxylate
  • a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid
Comment(s)
The enzyme is involved in the sphingolipid metabolism in the epidermis.
Cross-references
BRENDA3.5.1.109
EC2PDB3.5.1.109
ExplorEnz3.5.1.109
KEGG Ligand Database for Enzyme Nomenclature3.5.1.109
IUBMB Enzyme Nomenclature3.5.1.109
MEDLINEFind literature relating to 3.5.1.109
MetaCyc3.5.1.109
Rhea expert-curated reactions3.5.1.109
UniProtKB/Swiss-Prot
Q13510, ASAH1_HUMAN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-