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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.5.1.113

Accepted Name
2'''-acetyl-6'''-hydroxyneomycin C deacetylase.
Reaction catalysed
2'''-acetyl-6'''-deamino-6'''-hydroxyneomycin C + H(2)O <=> 6'''-deamino-6'''-hydroxyneomycin C + acetate
Comment(s)
  • Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family.
  • The enzyme from the bacterium Streptomyces fradiae also catalyzes EC 3.5.1.112.
Cross-references
BRENDA3.5.1.113
EC2PDB3.5.1.113
ExplorEnz3.5.1.113
PRIAM enzyme-specific profiles3.5.1.113
KEGG Ligand Database for Enzyme Nomenclature3.5.1.113
IUBMB Enzyme Nomenclature3.5.1.113
IntEnz3.5.1.113
MEDLINEFind literature relating to 3.5.1.113
MetaCyc3.5.1.113
UniProtKB/Swiss-Prot
Q53U10, NEOL_STRFR

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-