ID   3.5.1.133
DE   N(alpha)-acyl-L-glutamine aminoacylase.
AN   AMRE.
AN   axillary malodor releasing enzyme.
CA   an N(2)-acyl-L-glutamine + H2O = a carboxylate + L-glutamine.
CC   -!- Requires Zn(2+).
CC   -!- The enzyme, characterized from the bacterium Corynebacterium sp.Ax20,
CC       hydrolyzes odorless N(alpha)-acyl-L-glutamine conjugates of short-
CC       and medium-chain fatty acids, releasing axillary malodor compounds.
CC   -!- While the enzyme is highly specific for the L-glutamine moiety, it is
CC       quite promiscuous regarding the acyl moiety.
CC   -!- The two most common products of the enzyme's activity in axillary
CC       secretions are (2E)-3-methylhex-2-enoate and 3-hydroxy-3-
CC       methylhexanoate.
DR   Q8GGD4, AGAA_CORST ;
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