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ENZYME entry: EC 3.5.1.135

Accepted Name
N(4)-acetylcytidine amidohydrolase.
Reaction catalysed
N(4)-acetylcytidine + H(2)O <=> cytidine + acetate
Comment(s)
  • The enzyme from the bacterium Escherichia coli is one of the smallest known monomeric amidohydrolases (103-amino acids).
  • The enzyme is active toward a wide range of N(4)- acylcytosines/cytidines, but is by far most active against N(4)- acetylcytidine.
Cross-references
BRENDA3.5.1.135
EC2PDB3.5.1.135
ExplorEnz3.5.1.135
PRIAM enzyme-specific profiles3.5.1.135
KEGG Ligand Database for Enzyme Nomenclature3.5.1.135
IUBMB Enzyme Nomenclature3.5.1.135
IntEnz3.5.1.135
MEDLINEFind literature relating to 3.5.1.135
MetaCyc3.5.1.135
Rhea expert-curated reactions3.5.1.135
UniProtKB/Swiss-Prot
A8APA8, AC4CH_CITK8;  A7MR71, AC4CH_CROS8;  A7ZR09, AC4CH_ECO24;  
B7UHU9, AC4CH_ECO27;  B7MM87, AC4CH_ECO45;  B7LF85, AC4CH_ECO55;  
P67604, AC4CH_ECO57;  B5YQ93, AC4CH_ECO5E;  B7NHW2, AC4CH_ECO7I;  
B7MZJ8, AC4CH_ECO81;  B7LYG4, AC4CH_ECO8A;  C5A0H2, AC4CH_ECOBW;  
B1XEI7, AC4CH_ECODH;  A8A441, AC4CH_ECOHS;  A1AF90, AC4CH_ECOK1;  
Q0TDV1, AC4CH_ECOL5;  Q8FE69, AC4CH_ECOL6;  B1ITA2, AC4CH_ECOLC;  
P67603, AC4CH_ECOLI;  B7N7E4, AC4CH_ECOLU;  B6I733, AC4CH_ECOSE;  
B1LDA1, AC4CH_ECOSM;  Q1R7D0, AC4CH_ECOUT;  C5BGW5, AC4CH_EDWI9;  
B7LPB4, AC4CH_ESCF3;  Q4QKA6, AC4CH_HAEI8;  A5UC01, AC4CH_HAEIE;  
P44172, AC4CH_HAEIN;  B5XUE4, AC4CH_KLEP3;  A6TDQ4, AC4CH_KLEP7;  
Q9RA13, AC4CH_MORMI;  Q9CL02, AC4CH_PASMU;  B5F5H4, AC4CH_SALA4;  
A9MRH4, AC4CH_SALAR;  Q57K65, AC4CH_SALCH;  B5FUG3, AC4CH_SALDC;  
B5QXH7, AC4CH_SALEP;  B5RE11, AC4CH_SALG2;  B4TGX0, AC4CH_SALHS;  
B4T545, AC4CH_SALNS;  Q5PJF2, AC4CH_SALPA;  A9N3M7, AC4CH_SALPB;  
C0PY23, AC4CH_SALPC;  B5BFL5, AC4CH_SALPK;  B4TUR7, AC4CH_SALSV;  
Q8Z3X3, AC4CH_SALTI;  Q8ZM79, AC4CH_SALTY;  A8GFL3, AC4CH_SERP5;  
B8E759, AC4CH_SHEB2;  A3D5K4, AC4CH_SHEB5;  A6WPB5, AC4CH_SHEB8;  
A9L543, AC4CH_SHEB9;  Q8EFP8, AC4CH_SHEON;  A4Y7R6, AC4CH_SHEPC;  
A0KVW5, AC4CH_SHESA;  Q0HJR6, AC4CH_SHESM;  Q0HW12, AC4CH_SHESR;  
A1RIS2, AC4CH_SHESW;  B2U0R7, AC4CH_SHIB3;  Q31WG2, AC4CH_SHIBS;  
Q32BW4, AC4CH_SHIDS;  Q3YXX0, AC4CH_SHISS;  B7VN21, AC4CH_VIBA3;  
A5F7V7, AC4CH_VIBC3;  A7N681, AC4CH_VIBCB;  Q9KRR0, AC4CH_VIBCH;  
C3LMQ4, AC4CH_VIBCM;  Q87GA3, AC4CH_VIBPA;  Q8D7V1, AC4CH_VIBVU;  
Q7MEW6, AC4CH_VIBVY;  A1JLM9, AC4CH_YERE8;  A7FJ89, AC4CH_YERP3;  
Q1C8V5, AC4CH_YERPA;  B2K0H6, AC4CH_YERPB;  Q8ZFD6, AC4CH_YERPE;  
A9R5W6, AC4CH_YERPG;  Q1CH57, AC4CH_YERPN;  A4TKC4, AC4CH_YERPP;  
Q66BW2, AC4CH_YERPS;  B1JP35, AC4CH_YERPY;  

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