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ENZYME

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ENZYME entry: EC 3.5.1.38

Accepted Name
glutamin-(asparagin-)ase
Alternative Name(s)
glutaminase-asparaginase
L-ASNase/L-GLNase
L-asparagine/L-glutamine amidohydrolase
Reaction catalysed
  • H2O + L-glutamine = L-glutamate + NH4(+)
  • H2O + L-asparagine = L-aspartate + NH4(+)
Comment(s)
  • L-asparagine is hydrolyzed at 0.8 of the rate of L-glutamine.
  • The D-isomers are also hydrolyzed, more slowly. cf. EC 3.5.1.1 and EC 3.5.1.2.
Cross-references
BRENDA3.5.1.38
EC2PDB3.5.1.38
ExplorEnz3.5.1.38
PRIAM enzyme-specific profiles3.5.1.38
KEGG Ligand Database for Enzyme Nomenclature3.5.1.38
IUBMB Enzyme Nomenclature3.5.1.38
IntEnz3.5.1.38
MEDLINEFind literature relating to 3.5.1.38
MetaCyc3.5.1.38
Rhea expert-curated reactions3.5.1.38
UniProtKB/Swiss-Prot
P10172, ASPQ_ACIGLP83712, ASPQ_DELACQ9I407, ASPQ_PSEAE
O68897, ASPQ_PSEFAQ88K39, ASPQ_PSEPKP10182, ASPQ_PSES7

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-