ENZYME entry: EC 3.5.1.5

PURL: https://purl.expasy.org/enzyme/EC/3.5.1.5

Accepted Name

urease

Reaction catalysed

urea + 2 H2O + H(+) = hydrogencarbonate + 2 NH4(+)

Comment(s)

A nickel protein.
Urease catalyzes the hydrolysis of urea to yield ammonia and carbamate, which spontaneously hydrolyzes to form carbonic acid and a second molecule of ammonia.
In aqueous solutions the products convert to ammonium and hydrogen carbonate.
The enzyme is widespread and is found in many bacteria, some archaea, and many eukaryotes, including plants, some invertebrates, and numerous eukaryotic microorganisms.
Urease is one of the earlier enzymes to be studied, first obtained In 1874, and named urease in 1890.
The crystallization of urease in 1926 was a significant landmark in biochemistry, showing for the first time ever that enzymes are proteins and can be crystallized.
In 1975 it was found that the enzyme contains nickel ions in its active site.

Cross-references

Rhea expert-curated reactions

3.5.1.5

ExplorEnz

3.5.1.5

IUBMB Enzyme Nomenclature

3.5.1.5

UniProtKB/Swiss-Prot

Q2YPD5, URE11_BRUA2	Q93T81, URE11_BRUAB	Q8YF72, URE11_BRUME
Q8G2P8, URE11_BRUSU	Q4ZUD2, URE11_PSEU2	Q1QCE0, URE11_PSYCK
Q82JN9, URE11_STRAW	Q9FCD3, URE11_STRCO	Q2YQD8, URE12_BRUA2
Q57CE8, URE12_BRUAB	Q8YHZ8, URE12_BRUME	Q8FZW2, URE12_BRUSU
Q4ZN06, URE12_PSEU2	Q1QC36, URE12_PSYCK	Q826R9, URE12_STRAW
O86508, URE12_STRCO	A3DGF8, URE1_ACET2	Q6FD83, URE1_ACIAD
A3N2R4, URE1_ACTP2	B3H2L3, URE1_ACTP7	B0BRU2, URE1_ACTPJ
O54420, URE1_ACTPL	Q8UCT2, URE1_AGRFC	Q21SZ2, URE1_ALBFT
Q0VKY1, URE1_ALCBS	A8ESZ8, URE1_ALIB4	Q5E728, URE1_ALIF1
B5FBC6, URE1_ALIFM	B9JR81, URE1_ALLAM	B4RSX9, URE1_ALTMD
A7HHN1, URE1_ANADF	B4UFU2, URE1_ANASK	A0JRH4, URE1_ARTS2
B6YQL8, URE1_AZOPC	A1KBB4, URE1_AZOSB	Q733J6, URE1_BACC1
Q07397, URE1_BACSB	P77837, URE1_BACSU	A7Z9N4, URE1_BACVZ
B2IIJ1, URE1_BEII9	Q7VRS6, URE1_BLOFL	Q492E9, URE1_BLOPB
O08400, URE1_BORBR	Q7W417, URE1_BORPA	Q7VUD3, URE1_BORPE
Q89UG0, URE1_BRADU	B1YUF9, URE1_BURA4	A0K576, URE1_BURCH
B4ECC7, URE1_BURCJ	Q0BHN5, URE1_BURCM	Q39IW3, URE1_BURL3
A9AF72, URE1_BURM1	A3MMV2, URE1_BURM7	A2S996, URE1_BURM9
Q62HS0, URE1_BURMA	A1V1G6, URE1_BURMS	B1JX29, URE1_BURO0
Q1BYH2, URE1_BURO1	A3NYC9, URE1_BURP0	Q3JPJ6, URE1_BURP1
A3NCL7, URE1_BURP6	Q63RL3, URE1_BURPS	Q2SYF7, URE1_BURTA
A4JC42, URE1_BURVG	A4XMA9, URE1_CALS8	Q5FB23, URE1_CAMLA
A3PL38, URE1_CERS1	Q3J154, URE1_CERS4	A4WR75, URE1_CERS5
B9KK46, URE1_CERSK	Q11EW4, URE1_CHESB	A8APV0, URE1_CITK8
P94669, URE1_CLOPF	Q8FQX2, URE1_COREF	Q79VJ3, URE1_CORGL
B1VHT2, URE1_CORU7	Q0KCP6, URE1_CUPNH	Q473Q9, URE1_CUPPJ
B8HW50, URE1_CYAP4	Q11VN3, URE1_CYTH3	Q47G55, URE1_DECAR
Q9RYJ4, URE1_DEIRA	A9BUC4, URE1_DELAS	A8LRS0, URE1_DINSH
Q8XAG0, URE1_ECO57	B5YUX3, URE1_ECO5E	Q03284, URE1_ECOLX
C5BBR6, URE1_EDWI9	A4WEJ5, URE1_ENT38	A5FAD1, URE1_FLAJ1
Q0RQS0, URE1_FRAAA	Q2JES6, URE1_FRACC	Q5KYM1, URE1_GEOKA
B7K912, URE1_GLOC7	Q4QN09, URE1_HAEI8	A5U9V6, URE1_HAEIE
A5UH45, URE1_HAEIG	P44391, URE1_HAEIN	Q2SDQ1, URE1_HAHCH
Q9KG59, URE1_HALH5	Q75ZQ5, URE1_HALMA	Q18EB9, URE1_HALWD
Q08716, URE1_HELFC	P42823, URE1_HELHE	Q93PJ4, URE1_HELHP
P50045, URE1_HELMU	B6JPH5, URE1_HELP2	B5Z674, URE1_HELPG
Q1CV82, URE1_HELPH	P69997, URE1_HELPJ	B2UW70, URE1_HELPS
P69996, URE1_HELPY	A9AZE6, URE1_HERA2	A6SZ07, URE1_JANMA
Q28RJ3, URE1_JANSC	P18314, URE1_KLEAE	A6TE42, URE1_KLEP7
B5XU27, URE1_KLEV3	B2GI06, URE1_KOCRD	A9KJR9, URE1_LACP7
C1D5Z8, URE1_LARHH	B1Y3V1, URE1_LEPCP	P26929, URE1_LIMFE
A0L6F2, URE1_MAGMM	A6VTV8, URE1_MARMS	A1U4Z8, URE1_MARN8
Q1H0F2, URE1_METFK	A2SDJ0, URE1_METPP	B8EPU9, URE1_METSB
B0JKA1, URE1_MICAN	C5C8U3, URE1_MICLC	P17337, URE1_MORMO
B1MB85, URE1_MYCA9	P0A661, URE1_MYCBO	A1KJR2, URE1_MYCBP
C1APC7, URE1_MYCBT	B2HSZ2, URE1_MYCMM	A0QYE0, URE1_MYCS2
A3Q0D5, URE1_MYCSJ	A1UGT5, URE1_MYCSK	Q1B872, URE1_MYCSS
A5U3L7, URE1_MYCTA	P9WFF0, URE1_MYCTO	P9WFF1, URE1_MYCTU
A0PSG2, URE1_MYCUA	A1T9N4, URE1_MYCVP	Q3IRZ5, URE1_NATPD
Q2Y9M7, URE1_NITMU	Q3J770, URE1_NITOC	Q5YWR8, URE1_NOCFA
B2IT66, URE1_NOSP7	Q8YQZ0, URE1_NOSS1	B1ZP06, URE1_OPITP
A1R1C5, URE1_PAEAT	A1TSZ6, URE1_PARC0	A1B1B9, URE1_PARDP
Q7U3I3, URE1_PARMW	A8L7B0, URE1_PARS2	P50046, URE1_PHODD
Q7N4Y7, URE1_PHOLL	A4SY44, URE1_POLAQ	A1VKW3, URE1_POLNA
Q12DU3, URE1_POLSJ	P16122, URE1_PROHU	A3PCP1, URE1_PROM0
A2C4S2, URE1_PROM1	A8G4K9, URE1_PROM2	A2CE01, URE1_PROM3
Q31B49, URE1_PROM9	P17086, URE1_PROMH	Q7V3V2, URE1_PROMM
Q7V1B6, URE1_PROMP	A2BQW8, URE1_PROMS	Q46IY3, URE1_PROMT
Q9L644, URE1_PROS9	Q48DE6, URE1_PSE14	Q9HUU5, URE1_PSEAE
B8HA07, URE1_PSECP	Q1IBP0, URE1_PSEE4	Q4KJ10, URE1_PSEF5
A5W4B6, URE1_PSEP1	Q3KIT2, URE1_PSEPF	B0KUZ7, URE1_PSEPG
Q88J04, URE1_PSEPK	B1J815, URE1_PSEPW	Q87VP0, URE1_PSESM
Q3IH68, URE1_PSET1	A1SYY1, URE1_PSYIN	Q8XXT1, URE1_RALN1
B3PXB3, URE1_RHIE6	Q2K517, URE1_RHIEC	Q1MCV9, URE1_RHIJ3
Q98CY9, URE1_RHILO	B5ZMP0, URE1_RHILW	P42885, URE1_RHIME
B9J8M3, URE1_RHIR8	Q0S4S7, URE1_RHOJR	C1AXZ2, URE1_RHOOB
Q2IZ49, URE1_RHOP2	Q07K73, URE1_RHOP5	Q6N3N3, URE1_RHOPA
Q210F9, URE1_RHOPB	Q133L6, URE1_RHOPS	B3QGK1, URE1_RHOPT
Q161S8, URE1_ROSDO	Q5LSQ2, URE1_RUEPO	Q1GJP8, URE1_RUEST
Q21P94, URE1_SACD2	B0TT71, URE1_SHEHH	C3MGI5, URE1_SINFN
A6UC35, URE1_SINMW	A9GP84, URE1_SORC5	P41020, URE1_SPOPA
A7X5M3, URE1_STAA1	A6U414, URE1_STAA2	Q2FEK3, URE1_STAA3
Q2G2K5, URE1_STAA8	A5IV71, URE1_STAA9	Q2YYQ6, URE1_STAAB
Q5HDR8, URE1_STAAC	A6QJD0, URE1_STAAE	P67403, URE1_STAAM
P67404, URE1_STAAN	Q6GEE4, URE1_STAAR	Q6G732, URE1_STAAS
A8Z387, URE1_STAAT	P67405, URE1_STAAW	B9DLY0, URE1_STACT
Q5HLW1, URE1_STAEQ	Q8CNC9, URE1_STAES	Q4A0J5, URE1_STAS1
P42873, URE1_STAXY	P50047, URE1_STRE5	Q5M1G6, URE1_STRT1
Q5M607, URE1_STRT2	Q03ME3, URE1_STRTD	Q972W0, URE1_SULTO
Q2JWP0, URE1_SYNJA	Q2JQ88, URE1_SYNJB	O87402, URE1_SYNPV
A5GWV7, URE1_SYNR3	Q0I656, URE1_SYNS3	Q3AVR1, URE1_SYNS9
Q3AGD0, URE1_SYNSC	P73061, URE1_SYNY3	C5BUN9, URE1_TERTT
Q8DMV6, URE1_THEVB	C4LF63, URE1_TOLAT	Q117Z3, URE1_TRIEI
Q3M712, URE1_TRIV2	B1AJ73, URE1_UREP2	P0C7K7, URE1_UREPA
B5ZBS9, URE1_UREU1	P0CB00, URE1_UREUR	C5CY00, URE1_VARPS
A1WIM3, URE1_VEREI	A1JKD9, URE1_YERE8	P31494, URE1_YEREN
A7FFN2, URE1_YERP3	Q1C5B3, URE1_YERPA	B2KAA4, URE1_YERPB
Q9ZFR9, URE1_YERPE	A9R3V0, URE1_YERPG	Q1CKJ9, URE1_YERPN
A4TL32, URE1_YERPP	P52313, URE1_YERPS	B1JR71, URE1_YERPY
Q2YPD6, URE21_BRUA2	P0C1D5, URE21_BRUAB	Q7CNT2, URE21_BRUME
Q8G2P9, URE21_BRUSU	Q2YQD9, URE22_BRUA2	Q57CE9, URE22_BRUAB
Q8YHZ7, URE22_BRUME	Q8FZW3, URE22_BRUSU	Q5FB24, URE23_CAMLA
Q9RYJ3, URE23_DEIRA	Q17VS7, URE23_HELAH	Q8GH98, URE23_HELBI
Q08715, URE23_HELFE	P42822, URE23_HELHE	Q93PJ5, URE23_HELHP
P50044, URE23_HELMU	B6JPH6, URE23_HELP2	Q1CV81, URE23_HELPH
Q9ZMZ4, URE23_HELPJ	B2UW71, URE23_HELPS	P14916, URE23_HELPY
Q883F3, URE23_PSESM	Q4ZUD1, URE23_PSEU2	Q82JN8, URE23_STRAW
O86507, URE23_STRCO	Q972V9, URE23_SULTO	B0C793, URE2_ACAM1
A3DGF9, URE2_ACET2	Q6FD84, URE2_ACIAD	B7GXU4, URE2_ACIB3
B7I8T4, URE2_ACIB5	B2HVR9, URE2_ACIBC	B0VSC1, URE2_ACIBS
A3M3F1, URE2_ACIBT	B0V9P6, URE2_ACIBY	A3N2R5, URE2_ACTP2
B3H2L4, URE2_ACTP7	B0BRU3, URE2_ACTPJ	O54419, URE2_ACTPL
Q8UCS8, URE2_AGRFC	Q21SZ4, URE2_ALBFT	Q0VKY0, URE2_ALCBS
Q5E727, URE2_ALIF1	B5FBC7, URE2_ALIFM	Q0AC99, URE2_ALKEH
B9JR84, URE2_ALLAM	B4RSX8, URE2_ALTMD	A0JRH3, URE2_ARTS2
A1KBB5, URE2_AZOSB	C1DNK5, URE2_AZOVD	Q733J5, URE2_BACC1
Q07398, URE2_BACSB	P71035, URE2_BACSU	A7Z9N5, URE2_BACVZ
Q7VRS5, URE2_BLOFL	Q492E8, URE2_BLOPB	P0A4R2, URE2_BORBR
P0A4R3, URE2_BORPA	Q7VUD2, URE2_BORPE	Q89UG2, URE2_BRADU
A5ERV2, URE2_BRASB	A4YM26, URE2_BRASO	B1YUG0, URE2_BURA4
A0K577, URE2_BURCH	B4ECC6, URE2_BURCJ	Q0BHN4, URE2_BURCM
Q39IW2, URE2_BURL3	A9AF71, URE2_BURM1	A3MMV1, URE2_BURM7
A2S997, URE2_BURM9	Q62HS1, URE2_BURMA	A1V1G7, URE2_BURMS
B1JX30, URE2_BURO0	Q1BYH1, URE2_BURO1	A3NYC8, URE2_BURP0
Q3JPJ7, URE2_BURP1	A3NCL6, URE2_BURP6	Q63RL4, URE2_BURPS
Q2SYF6, URE2_BURTA	A4JC43, URE2_BURVG	A3PL41, URE2_CERS1
Q3J151, URE2_CERS4	A4WR73, URE2_CERS5	B9KK50, URE2_CERSK
Q11EW5, URE2_CHESB	Q1QV52, URE2_CHRI1	A8APU9, URE2_CITK8
P94668, URE2_CLOPF	Q8FQX3, URE2_COREF	A4QA22, URE2_CORGB
Q79VJ4, URE2_CORGL	Q1LPT0, URE2_CUPMC	Q0KCP7, URE2_CUPNH
Q473R0, URE2_CUPPJ	B3R401, URE2_CUPTR	B8HW51, URE2_CYAP4
Q47G54, URE2_DECAR	A8LRS3, URE2_DINSH	Q8XAG1, URE2_ECO57
B5YUX2, URE2_ECO5E	Q03283, URE2_ECOLX	A4XQ45, URE2_ECTM1
A4WEJ4, URE2_ENT38	A5FAD2, URE2_FLAJ1	Q0RQR9, URE2_FRAAA
Q2JES5, URE2_FRACC	Q5KYM0, URE2_GEOKA	B7K907, URE2_GLOC7
Q0BQ41, URE2_GRABC	Q4QN08, URE2_HAEI8	A5U9V5, URE2_HAEIE
P44392, URE2_HAEIN	Q2SDQ2, URE2_HAHCH	Q9KG60, URE2_HALH5
Q75ZQ6, URE2_HALMA	Q18EC0, URE2_HALWD	A9AZE7, URE2_HERA2
A6SZ06, URE2_JANMA	Q28RJ8, URE2_JANSC	P18315, URE2_KLEAE
A6TE41, URE2_KLEP7	B5XU28, URE2_KLEV3	B2GI07, URE2_KOCRD
A9KJS0, URE2_LACP7	B1Y3V2, URE2_LEPCP	P26930, URE2_LIMFE
B1HZE3, URE2_LYSSC	A0L6F1, URE2_MAGMM	A6VTV7, URE2_MARMS
A1U4Z9, URE2_MARN8	Q1H0F1, URE2_METFK	A2SDJ1, URE2_METPP
B8EPV0, URE2_METSB	B0JTP2, URE2_MICAN	C5C8U2, URE2_MICLC
P17338, URE2_MORMO	P0A663, URE2_MYCBO	A1KJR1, URE2_MYCBP
C1APC6, URE2_MYCBT	B2HSZ1, URE2_MYCMM	A3Q0D6, URE2_MYCSJ
A1UGT6, URE2_MYCSK	Q1B871, URE2_MYCSS	A5U3L6, URE2_MYCTA
P9WFE8, URE2_MYCTO	P9WFE9, URE2_MYCTU	A0PSG3, URE2_MYCUA
A1T9N5, URE2_MYCVP	Q3IRZ6, URE2_NATPD	Q2Y9M8, URE2_NITMU
Q3J769, URE2_NITOC	Q5YWR9, URE2_NOCFA	B2IT65, URE2_NOSP7
Q8YQZ2, URE2_NOSS1	B1ZP07, URE2_OPITP	A1R1C4, URE2_PAEAT
A1TSZ5, URE2_PARC0	Q7U3I4, URE2_PARMW	B2JF66, URE2_PARP8
B2T0P6, URE2_PARPJ	Q144E3, URE2_PARXL	Q7N4Y8, URE2_PHOLL
A1VKW4, URE2_POLNA	Q12DU2, URE2_POLSJ	P16123, URE2_PROHU
A3PCP0, URE2_PROM0	A2C4S1, URE2_PROM1	A8G4K8, URE2_PROM2
A2CE00, URE2_PROM3	Q31B50, URE2_PROM9	P17087, URE2_PROMH
Q7V3V3, URE2_PROMM	Q7V1B5, URE2_PROMP	A2BQW7, URE2_PROMS
Q46IY4, URE2_PROMT	Q48DE7, URE2_PSE14	B7V1T0, URE2_PSEA8
Q02FF2, URE2_PSEAB	Q9HUU6, URE2_PSEAE	B8HA06, URE2_PSECP
Q1IBP1, URE2_PSEE4	Q4KJ09, URE2_PSEF5	C3K5A2, URE2_PSEFS
A6VCX4, URE2_PSEP7	Q3KIT1, URE2_PSEPF	B0KUZ8, URE2_PSEPG
Q88J05, URE2_PSEPK	B1J814, URE2_PSEPW	Q87VP1, URE2_PSESM
Q3IH69, URE2_PSET1	Q4ZN07, URE2_PSEU2	Q1QCE1, URE2_PSYCK
A1SYY0, URE2_PSYIN	Q8XXT0, URE2_RALN1	B2U7N2, URE2_RALPJ
B3PXB6, URE2_RHIE6	Q2K514, URE2_RHIEC	Q1MCV6, URE2_RHIJ3
Q98CY6, URE2_RHILO	B5ZMP3, URE2_RHILW	P42886, URE2_RHIME
B9J8M5, URE2_RHIR8	Q0S4S8, URE2_RHOJR	C1AXZ1, URE2_RHOOB
Q2IZ51, URE2_RHOP2	Q07K71, URE2_RHOP5	Q6N3N1, URE2_RHOPA
Q210F6, URE2_RHOPB	Q133L3, URE2_RHOPS	B3QGK3, URE2_RHOPT
Q161T1, URE2_ROSDO	Q5LSQ3, URE2_RUEPO	Q1GJP7, URE2_RUEST
Q21P95, URE2_SACD2	A4F7F6, URE2_SACEN	B0TT70, URE2_SHEHH
C3MGX4, URE2_SINFN	A6UC38, URE2_SINMW	P41021, URE2_SPOPA
A7X5M0, URE2_STAA1	A6U413, URE2_STAA2	Q2FEK4, URE2_STAA3
Q2G2K6, URE2_STAA8	A5IV70, URE2_STAA9	Q2YYQ7, URE2_STAAB
Q5HDR9, URE2_STAAC	A6QJC9, URE2_STAAE	P67406, URE2_STAAM
P67407, URE2_STAAN	Q6GEE5, URE2_STAAR	Q6G733, URE2_STAAS
A8Z386, URE2_STAAT	Q8NV90, URE2_STAAW	B9DLX9, URE2_STACT
Q5HLW2, URE2_STAEQ	Q8CND0, URE2_STAES	Q4A0J4, URE2_STAS1
P42874, URE2_STAXY	Q826S0, URE2_STRAW	Q9FCD2, URE2_STRCO
Q55054, URE2_STRE5	B1W5G8, URE2_STRGG	Q5M1G7, URE2_STRT1
Q5M608, URE2_STRT2	Q03ME4, URE2_STRTD	A4VQV0, URE2_STUS1
O87401, URE2_SYNPV	A5GWV6, URE2_SYNR3	Q0I657, URE2_SYNS3
Q3AVR2, URE2_SYNS9	Q3AGD1, URE2_SYNSC	P74386, URE2_SYNY3
C5BUP0, URE2_TERTT	Q8DLZ6, URE2_THEVB	B8GQ25, URE2_THISH
C4LF64, URE2_TOLAT	Q117Z8, URE2_TRIEI	Q3M710, URE2_TRIV2
B1AJ74, URE2_UREP2	P0C7K8, URE2_UREPA	B5ZBT0, URE2_UREU1
P0CB01, URE2_UREUR	C5CXZ9, URE2_VARPS	A1WIM4, URE2_VEREI
A1JKD8, URE2_YERE8	P31495, URE2_YEREN	A7FFN1, URE2_YERP3
P69990, URE2_YERPE	P69991, URE2_YERPS	Q2YPD7, URE31_BRUA2
P0C121, URE31_BRUAB	Q8YF71, URE31_BRUME	Q8G2Q0, URE31_BRUSU
Q1QCE2, URE31_PSYCK	Q2YQE0, URE32_BRUA2	Q57CF0, URE32_BRUAB
Q8YHZ6, URE32_BRUME	Q8FZW4, URE32_BRUSU	Q1QC34, URE32_PSYCK
B0C791, URE3_ACAM1	A3DGG0, URE3_ACET2	Q6FD85, URE3_ACIAD
B7GXU5, URE3_ACIB3	B7I8T3, URE3_ACIB5	B2HVR8, URE3_ACIBC
B0VSC2, URE3_ACIBS	A3M3F0, URE3_ACIBT	B0V9P7, URE3_ACIBY
Q9Z395, URE3_ACTNA	A3N2R6, URE3_ACTP2	B3H2L5, URE3_ACTP7
B0BRU4, URE3_ACTPJ	O54418, URE3_ACTPL	Q8UCS6, URE3_AGRFC
Q21SZ5, URE3_ALBFT	Q0VKX9, URE3_ALCBS	Q5E726, URE3_ALIF1
B5FBC8, URE3_ALIFM	Q0ACA0, URE3_ALKEH	B9JR86, URE3_ALLAM
B4RSX7, URE3_ALTMD	A0JRH2, URE3_ARTS2	A1KBB7, URE3_AZOSB
C1DNK6, URE3_AZOVD	Q733J4, URE3_BACC1	Q07399, URE3_BACSB
P75030, URE3_BACSU	Q7VRS4, URE3_BLOFL	Q492E7, URE3_BLOPB
P0A4U0, URE3_BORBR	P0A4U1, URE3_BORPA	Q7VUD0, URE3_BORPE
Q89UG3, URE3_BRADU	B1YUG1, URE3_BURA4	A0K578, URE3_BURCH
B4ECC5, URE3_BURCJ	Q0BHN3, URE3_BURCM	Q39IW1, URE3_BURL3
A9AF70, URE3_BURM1	A3MMV0, URE3_BURM7	A2S998, URE3_BURM9
Q62HS2, URE3_BURMA	A1V1G8, URE3_BURMS	B1JX31, URE3_BURO0
Q1BYH0, URE3_BURO1	A3NYC7, URE3_BURP0	Q3JPJ8, URE3_BURP1
A3NCL5, URE3_BURP6	Q63RL5, URE3_BURPS	Q2SYF5, URE3_BURTA
A4JC44, URE3_BURVG	A3PL42, URE3_CERS1	Q9RFF5, URE3_CERS4
A4WR72, URE3_CERS5	B9KK51, URE3_CERSK	Q11EW7, URE3_CHESB
Q1QV51, URE3_CHRI1	A8APU8, URE3_CITK8	P94667, URE3_CLOPF
Q8FQX4, URE3_COREF	A4QA21, URE3_CORGB	Q9RHM6, URE3_CORGL
C4LIA9, URE3_CORK4	B1VHT0, URE3_CORU7	Q1LPT2, URE3_CUPMC
O30334, URE3_CUPNH	Q473R2, URE3_CUPPJ	B3R3Z9, URE3_CUPTR
B8HW52, URE3_CYAP4	Q47G53, URE3_DECAR	A9BUC7, URE3_DELAS
A8LRS4, URE3_DINSH	Q8XAG2, URE3_ECO57	B5YUX1, URE3_ECO5E
Q03282, URE3_ECOLX	A4XQ47, URE3_ECTM1	C5BDC2, URE3_EDWI9
A4WEJ3, URE3_ENT38	A5FAD3, URE3_FLAJ1	Q0RQR8, URE3_FRAAA
Q2JES4, URE3_FRACC	Q5KYL9, URE3_GEOKA	B7K906, URE3_GLOC7
Q0BQ42, URE3_GRABC	Q4QN07, URE3_HAEI8	A5U9V4, URE3_HAEIE
A5UH46, URE3_HAEIG	P44393, URE3_HAEIN	Q2SDQ3, URE3_HAHCH
Q9KG61, URE3_HALH5	Q75ZQ4, URE3_HALMA	Q18EB8, URE3_HALWD
A9AZE8, URE3_HERA2	Q28RK0, URE3_JANSC	P18316, URE3_KLEAE
A6TE40, URE3_KLEP7	Q02943, URE3_KLEPN	B5XU29, URE3_KLEV3
B2GI08, URE3_KOCRD	A9KJS1, URE3_LACP7	C1D5Z6, URE3_LARHH
B1Y3V4, URE3_LEPCP	P26931, URE3_LIMFE	B1HZE2, URE3_LYSSC
A0L6F0, URE3_MAGMM	A6VTV6, URE3_MARMS	A1U500, URE3_MARN8
Q1H0F0, URE3_METFK	A2SDJ2, URE3_METPP	B8EPV1, URE3_METSB
B0JTP1, URE3_MICAN	C5C8U1, URE3_MICLC	P17339, URE3_MORMO
B1MB83, URE3_MYCA9	P0A677, URE3_MYCBO	A1KJR0, URE3_MYCBP
C1APC5, URE3_MYCBT	A4TAD3, URE3_MYCGI	A0QYE2, URE3_MYCS2
A3Q0D7, URE3_MYCSJ	A1UGT7, URE3_MYCSK	Q1B870, URE3_MYCSS
A5U3L5, URE3_MYCTA	P9WFE6, URE3_MYCTO	P9WFE7, URE3_MYCTU
A0PSG4, URE3_MYCUA	A1T9N6, URE3_MYCVP	Q3IRZ4, URE3_NATPD
Q2Y9M9, URE3_NITMU	Q3J768, URE3_NITOC	Q5YWS0, URE3_NOCFA
B2IT64, URE3_NOSP7	Q8YQZ3, URE3_NOSS1	B1ZP08, URE3_OPITP
A1R1C3, URE3_PAEAT	A1TSZ3, URE3_PARC0	A1B1C2, URE3_PARDP
Q7U3I5, URE3_PARMW	B2JF65, URE3_PARP8	B2T0P7, URE3_PARPJ
Q144E2, URE3_PARXL	Q7N4Y9, URE3_PHOLL	B1XLM3, URE3_PICP2
A4SY47, URE3_POLAQ	A1VKW6, URE3_POLNA	Q12DU1, URE3_POLSJ
P16124, URE3_PROHU	A3PCN9, URE3_PROM0	A2C4S0, URE3_PROM1
A8G4K7, URE3_PROM2	A2CDZ9, URE3_PROM3	Q31B51, URE3_PROM9
P17088, URE3_PROMH	Q7V3V4, URE3_PROMM	Q7V1B4, URE3_PROMP
A2BQW6, URE3_PROMS	Q46IY5, URE3_PROMT	Q9L642, URE3_PROS9
Q48DF0, URE3_PSE14	B7V1S8, URE3_PSEA8	Q02FF4, URE3_PSEAB
Q9HUU8, URE3_PSEAE	B8HA05, URE3_PSECP	Q1IBP2, URE3_PSEE4
Q4KJ06, URE3_PSEF5	C3K5A5, URE3_PSEFS	A5W4B8, URE3_PSEP1
A6VCX2, URE3_PSEP7	Q3KIS8, URE3_PSEPF	B0KUZ9, URE3_PSEPG
Q88J06, URE3_PSEPK	B1J813, URE3_PSEPW	Q87VP4, URE3_PSESM
Q3IH70, URE3_PSET1	Q4ZN10, URE3_PSEU2	A1SYX9, URE3_PSYIN
Q8XXS8, URE3_RALN1	B2U7N4, URE3_RALPJ	B3PXB8, URE3_RHIE6
Q2K512, URE3_RHIEC	Q1MCV5, URE3_RHIJ3	Q98CY3, URE3_RHILO
Q8RPY7, URE3_RHILV	B5ZMP5, URE3_RHILW	P42887, URE3_RHIME
B9J8M6, URE3_RHIR8	Q9AQT6, URE3_RHOCA	Q0S4S9, URE3_RHOJR
C1AXZ0, URE3_RHOOB	Q2IZ52, URE3_RHOP2	Q07K70, URE3_RHOP5
Q6N3N0, URE3_RHOPA	Q210F5, URE3_RHOPB	Q133L2, URE3_RHOPS
B3QGK4, URE3_RHOPT	Q161T2, URE3_ROSDO	Q5LSQ4, URE3_RUEPO
Q1GJP6, URE3_RUEST	Q21P96, URE3_SACD2	A4F7F5, URE3_SACEN
B0TT69, URE3_SHEHH	C3MGX6, URE3_SINFN	A6UC40, URE3_SINMW
P41022, URE3_SPOPA	A7X5L9, URE3_STAA1	A6U412, URE3_STAA2
Q2FEK5, URE3_STAA3	Q2FVW5, URE3_STAA8	A5IV69, URE3_STAA9
Q2YYQ8, URE3_STAAB	Q5HDS0, URE3_STAAC	A6QJC8, URE3_STAAE
P67718, URE3_STAAM	P67719, URE3_STAAN	Q6GEE6, URE3_STAAR
Q6G734, URE3_STAAS	A8Z385, URE3_STAAT	P67720, URE3_STAAW
B9DLX8, URE3_STACT	Q5HLW3, URE3_STAEQ	Q8CND1, URE3_STAES
Q4A0J3, URE3_STAS1	P42875, URE3_STAXY	Q826S1, URE3_STRAW
Q9FCD1, URE3_STRCO	Q55053, URE3_STRE5	B1W5G7, URE3_STRGG
Q5M1G8, URE3_STRT1	Q5M609, URE3_STRT2	Q03ME5, URE3_STRTD
Q83U21, URE3_STRTR	A4VQU9, URE3_STUS1	Q2JJ72, URE3_SYNJB
O87400, URE3_SYNPV	A5GWV5, URE3_SYNR3	Q0I658, URE3_SYNS3
Q3AVR3, URE3_SYNS9	Q3AGD2, URE3_SYNSC	P73796, URE3_SYNY3
C6AR50, URE3_TERTT	Q8DK85, URE3_THEVB	B8GQ24, URE3_THISH
C4LF65, URE3_TOLAT	Q117Z9, URE3_TRIEI	Q3M709, URE3_TRIV2
B1AJ75, URE3_UREP2	P0C7K9, URE3_UREPA	B5ZBT1, URE3_UREU1
P0CB02, URE3_UREUR	C5CXZ7, URE3_VARPS	A1WIM6, URE3_VEREI
Q9FAS7, URE3_VIBPH	Q6UR86, URE3_YERAL	Q6UR78, URE3_YERBE
A1JKD7, URE3_YERE8	P31496, URE3_YEREN	Q6UR70, URE3_YERFR
Q6UR62, URE3_YERIN	Q6UR53, URE3_YERKR	Q6UR44, URE3_YERMO
A7FFN0, URE3_YERP3	Q1C5B5, URE3_YERPA	B2KAA6, URE3_YERPB
P69994, URE3_YERPE	Q1CKK1, URE3_YERPN	A4TL34, URE3_YERPP
P69995, URE3_YERPS	B1JR69, URE3_YERPY	Q6UR35, URE3_YERRO
E6Y5X0, UREA2_CANEN	Q9SR52, UREA_ARATH	Q6A3P9, UREA_ASPFU
P07374, UREA_CANEN	P0CS22, UREA_CRYD1	P0CS23, UREA_CRYD3
O13465, UREA_CRYN9	E0ZS48, UREA_ORYSI	B9GCH9, UREA_ORYSJ
O00084, UREA_SCHPO	P08298, UREA_SOYBN

BRENDA

3.5.1.5

MetaCyc

3.5.1.5

KEGG Ligand Database for Enzyme Nomenclature

3.5.1.5

EC2PDB

3.5.1.5

MEDLINE

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