ENZYME entry: EC 3.5.1.79
Accepted Name |
Phthalyl amidase.
|
Alternative Name(s) |
o-phthalyl amidase. |
Reaction catalysed |
A phthalylamide + H(2)O <=> phthalic acid + a substituted amine |
Comment(s) |
- Phthalyl is used to mean 2-carboxybenzoyl.
- The enzyme from Xanthobacter agilis hydrolyzes phthalylated amino
acids, peptides, beta-lactams, aromatic and aliphatic amines.
- The substituent on nitrogen may be an alkyl group, but may also be
complex, giving an amino acid or peptide derivative.
- Substitutions on the phthalyl ring include 6-F, 6-NH(2), 3-OH, and a
nitrogen in the aromatic ring ortho to the carboxy group attached to
the amine.
|
Cross-references |
BRENDA | 3.5.1.79 |
EC2PDB | 3.5.1.79 |
ExplorEnz | 3.5.1.79 |
PRIAM enzyme-specific profiles | 3.5.1.79 |
KEGG Ligand Database for Enzyme Nomenclature | 3.5.1.79 |
IUBMB Enzyme Nomenclature | 3.5.1.79 |
IntEnz | 3.5.1.79 |
MEDLINE | Find literature relating to 3.5.1.79 |
MetaCyc | 3.5.1.79 |
UniProtKB/Swiss-Prot |
|
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