ID   3.5.1.87
DE   N-carbamoyl-L-amino-acid hydrolase.
AN   L-carbamoylase.
AN   L-N-carbamoylase.
AN   N-carbamoylase.
AN   N-carbamoyl L-amino acid amidohydrolase.
AN   N-carbamoyl-L-amino acid amidohydrolase.
CA   an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O = an L-alpha-amino acid
CA   + CO2 + NH4(+).
CC   -!- This enzyme, along with EC 3.5.1.77, EC 5.1.99.5 and EC 3.5.2.2,
CC       forms part of the reaction cascade known as the 'hydantoinase
CC       process', which allows the total conversion of D,L-5-monosubstituted
CC       hydantoins into optically pure D- or L-amino acids.
CC   -!- The enzyme from Alcaligenes xylosoxidans has broad specificity for
CC       carbamoyl-L-amino acids, although it is inactive on the carbamoyl
CC       derivatives of glutamate, aspartate, arginine, tyrosine or
CC       tryptophan.
CC   -!- The enzyme from Sinorhizobium meliloti requires a divalent cation for
CC       activity and can hydrolyze N-carbamoyl-L-tryptophan as well as
CC       N-carbamoyl L-amino acids with aliphatic substituents.
CC   -!- The enzyme is inactive on derivatives of D-amino acids.
CC   -!- In addition to N-carbamoyl L-amino acids, the enzyme can also
CC       hydrolyze formyl and acetyl derivatives to varying degrees.
DR   P37113, AMAB1_GEOSE;  Q53389, AMAB2_GEOSE;  Q9F464, HYUC_PAEAU ;
DR   Q01264, HYUC_PSESN ;  Q6DTN4, HYUC_RHIML ;
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