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ENZYME

ENZYME entry: EC 3.5.1.88

Accepted Name
peptide deformylase
Alternative Name(s)
PDF
polypeptide deformylase
Reaction catalysed
H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]
Comment(s)
  • Requires Fe(II).
  • Also requires at least a dipeptide for an efficient rate of reaction.
  • N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  • Differs in substrate specificity from EC 3.5.1.31.
Cross-references
BRENDA3.5.1.88
EC2PDB3.5.1.88
ExplorEnz3.5.1.88
PRIAM enzyme-specific profiles3.5.1.88
KEGG Ligand Database for Enzyme Nomenclature3.5.1.88
IUBMB Enzyme Nomenclature3.5.1.88
IntEnz3.5.1.88
MEDLINEFind literature relating to 3.5.1.88
MetaCyc3.5.1.88
Rhea expert-curated reactions3.5.1.88
UniProtKB/Swiss-Prot
Q9FV53, DEF1A_ARATHB6RGY0, DEF1A_ORYSJQ9FUZ0, DEF1A_SOLLC
Q9FUZ2, DEF1B_ARATHQ5VNN5, DEF1B_ORYSJQ9FV54, DEF1B_SOLLC
Q81WH1, DEF1_BACANQ819U0, DEF1_BACCRP94462, DEF1_BACSU
Q8G534, DEF1_BIFLOQ7WQS9, DEF1_BORBRQ7W1V3, DEF1_BORPA
Q7W0Q0, DEF1_BORPEA0A0H3KB98, DEF1_BURM1O05100, DEF1_CLOAB
Q8XJL2, DEF1_CLOPEQ8FT51, DEF1_COREFQ8NQ46, DEF1_CORGL
Q83CV9, DEF1_COXBUQ7NJV3, DEF1_GLOVIQ82TW4, DEF1_NITEU
Q8YSK6, DEF1_NOSS1Q7V8G6, DEF1_PROMMQ88RR1, DEF1_PSEPK
Q88B43, DEF1_PSESMQ8Y3B0, DEF1_RALN1Q92IZ1, DEF1_RICCN
Q8EKQ8, DEF1_SHEONQ82IV0, DEF1_STRAWQ9RD27, DEF1_STRCO
Q9KVU3, DEF1_VIBCHQ87KD5, DEF1_VIBPAQ8DDE3, DEF1_VIBVU
Q7MCQ2, DEF1_VIBVYQ8PGV2, DEF1_XANACQ8PCN7, DEF1_XANCP
Q81MQ9, DEF2_BACANQ819K2, DEF2_BACCRQ45495, DEF2_BACSU
Q8G487, DEF2_BIFLOQ7WG25, DEF2_BORBRQ7W4K0, DEF2_BORPA
Q7VS88, DEF2_BORPEQ97G95, DEF2_CLOABQ8XJX0, DEF2_CLOPE
Q8FMD0, DEF2_COREFQ8NM41, DEF2_CORGLQ83AK6, DEF2_COXBU
O31410, DEF2_GEOSEQ7NIF5, DEF2_GLOVIQ82TC8, DEF2_NITEU
Q8YVH1, DEF2_NOSS1Q7V5F9, DEF2_PROMMQ88EA7, DEF2_PSEPK
Q886I1, DEF2_PSESMQ8XZJ6, DEF2_RALN1Q92JI7, DEF2_RICCN
Q8EHZ2, DEF2_SHEONQ826Q0, DEF2_STRAWQ9FCA2, DEF2_STRCO
Q9KN16, DEF2_VIBCHQ87I22, DEF2_VIBPAQ8D5P5, DEF2_VIBVU
Q7MGK6, DEF2_VIBVYQ8PG20, DEF2_XANACQ8P4F9, DEF2_XANCP
Q8EE60, DEF3_SHEONQ825U9, DEF3_STRAWQ9XAQ2, DEF3_STRCO
Q9K4A0, DEF4_STRCOQ9HBH1, DEFM_HUMANS4R2K0, DEFM_MOUSE
A3DCX4, DEF_ACET2B0VNL8, DEF_ACIBSA0LUE1, DEF_ACIC1
C1F541, DEF_ACIC5B3GYT7, DEF_ACTP7A4ST57, DEF_AERS4
B6JJP8, DEF_AFIC5C4ZEV9, DEF_AGARVQ8UID1, DEF_AGRFC
Q0VTE1, DEF_ALCBSQ5E1Q8, DEF_ALIF1B5FCW6, DEF_ALIFM
B6EP21, DEF_ALISLQ0A5B9, DEF_ALKEHA6TRW8, DEF_ALKMQ
B4S291, DEF_ALTMDB3ETT4, DEF_AMOA5O66847, DEF_AQUAE
C1DFV8, DEF_AZOVDQ5LEQ9, DEF_BACFNQ64VP5, DEF_BACFR
Q8AAP4, DEF_BACTNA1UUB4, DEF_BARBKQ6G5F0, DEF_BARHE
Q6G1G6, DEF_BARQUA9ILK4, DEF_BART1Q1LT56, DEF_BAUCH
A1A2Z1, DEF_BIFAAQ7VQC0, DEF_BLOFLQ493I1, DEF_BLOPB
O51092, DEF_BORBUQ89BN9, DEF_BRADUC0QZQ2, DEF_BRAHW
A5ESQ7, DEF_BRASBA4YLB9, DEF_BRASOP63913, DEF_BRUME
P63914, DEF_BRUSUB8D9R9, DEF_BUCA5P57563, DEF_BUCAI
Q8K975, DEF_BUCAPB8D821, DEF_BUCATP59493, DEF_BUCBP
Q057D2, DEF_BUCCCB9MR36, DEF_CALBDQ8R9T0, DEF_CALS4
Q9PIT8, DEF_CAMJEQ3AC18, DEF_CARHZB0T1S9, DEF_CAUSK
Q9ABF5, DEF_CAUVCB8GYE3, DEF_CAUVNB3PGY7, DEF_CELJU
Q11LC7, DEF_CHESBA9WHG7, DEF_CHLAAQ5L6G8, DEF_CHLAB
B8G5R5, DEF_CHLADQ823U4, DEF_CHLCVQ253S4, DEF_CHLFF
B3EE19, DEF_CHLL2Q3B2U9, DEF_CHLL3Q9PK41, DEF_CHLMU
B3QPU5, DEF_CHLP8B3EPG5, DEF_CHLPBA1BHK0, DEF_CHLPD
A4SFP2, DEF_CHLPMQ9Z6J2, DEF_CHLPNB9LBS4, DEF_CHLSY
B0B7S2, DEF_CHLT2Q3KM05, DEF_CHLTAB0BBY7, DEF_CHLTB
Q8KCG7, DEF_CHLTEO84357, DEF_CHLTRA0M3P3, DEF_CHRFK
Q1QTJ5, DEF_CHRSDQ7NQ75, DEF_CHRVOA8AQI1, DEF_CITK8
O08450, DEF_CLOB8B2V4B1, DEF_CLOBAQ895Q2, DEF_CLOTE
A7MPE9, DEF_CROS8Q11X86, DEF_CYTH3Q3Z8F6, DEF_DEHM1
A5FRA7, DEF_DEHMBQ3ZXA9, DEF_DEHMCQ9RRQ4, DEF_DEIRA
C0QI55, DEF_DESAHB8FHH0, DEF_DESALB1I504, DEF_DESAP
B8FS81, DEF_DESHDQ24U09, DEF_DESHYA8ZUK5, DEF_DESOH
Q6AQ98, DEF_DESPSA5EWL8, DEF_DICNVB5YF46, DEF_DICT6
B8E0X7, DEF_DICTDB7UK10, DEF_ECO27B7MCQ2, DEF_ECO45
B7LHY3, DEF_ECO55P0A6K5, DEF_ECO57B5YT06, DEF_ECO5E
B7NLK6, DEF_ECO7IB7N171, DEF_ECO81B7M0Z2, DEF_ECO8A
C4ZUE1, DEF_ECOBWB1X6D9, DEF_ECODHA8A591, DEF_ECOHS
A1AGH8, DEF_ECOK1Q0TCH5, DEF_ECOL5P0A6K4, DEF_ECOL6
B1IQ13, DEF_ECOLCP0A6K3, DEF_ECOLIB7NDQ8, DEF_ECOLU
B6I200, DEF_ECOSEB1LGP3, DEF_ECOSMQ1R646, DEF_ECOUT
C5BF17, DEF_EDWI9B2KD65, DEF_ELUMPB1GZ10, DEF_ENDTX
A4WF95, DEF_ENT38Q82ZJ0, DEF_ENTFAB2VK93, DEF_ERWT9
Q2NCT3, DEF_ERYLHB7LRQ3, DEF_ESCF3B0S139, DEF_FINM2
A5FGV5, DEF_FLAJ1A6H0E7, DEF_FLAPJA8LE21, DEF_FRASN
Q8REF0, DEF_FUSNNB8F726, DEF_GLAP5Q7VKK9, DEF_HAEDU
Q4QMV6, DEF_HAEI8A5UEB4, DEF_HAEIEA5UH92, DEF_HAEIG
P44786, DEF_HAEINQ2SQX1, DEF_HAHCHQ9K9I9, DEF_HALH5
B8CWS6, DEF_HALOHC4K6Y0, DEF_HAMD5Q17XD4, DEF_HELAH
Q7VIN5, DEF_HELHPB0TGS8, DEF_HELMIB6JM24, DEF_HELP2
B5Z7F5, DEF_HELPGQ1CT77, DEF_HELPHQ9ZL51, DEF_HELPJ
B2UT38, DEF_HELPSP56419, DEF_HELPYQ0I181, DEF_HISS1
B0UWZ5, DEF_HISS2Q31J84, DEF_HYDCUQ0C4V1, DEF_HYPNA
Q5QXI5, DEF_IDILOA8Z5V9, DEF_KARMGB5XNC4, DEF_KLEP3
A6TEU0, DEF_KLEP7B3WE13, DEF_LACCBQ1GAR4, DEF_LACDA
Q04B51, DEF_LACDBQ042S1, DEF_LACGAA8YUR0, DEF_LACH4
Q74JW2, DEF_LACJOQ48661, DEF_LACLAQ039N7, DEF_LACP3
A9KM99, DEF_LACP7Q88VB2, DEF_LACPLQ38WP3, DEF_LATSS
B0SHH1, DEF_LEPBAQ04RW4, DEF_LEPBJQ051Q7, DEF_LEPBL
B0SQM2, DEF_LEPBPQ72S74, DEF_LEPICQ93LE9, DEF_LEPIN
Q03QL3, DEF_LEVBAQ1WU76, DEF_LIGS1B2GBA3, DEF_LIMF3
A5VJ71, DEF_LIMRDB2G6P1, DEF_LIMRJQ92CX8, DEF_LISIN
C1L1X2, DEF_LISMCQ721B5, DEF_LISMFB8DCF7, DEF_LISMH
Q8Y866, DEF_LISMOA0AHG3, DEF_LISW6B9EB04, DEF_MACCJ
Q8EVJ8, DEF_MALP2Q65QF2, DEF_MANSMQ0ASK2, DEF_MARMM
B3DUG9, DEF_METI4B8ENG6, DEF_METSBP94601, DEF_MICDP
Q2RK25, DEF_MOOTAB1MIN9, DEF_MYCA9Q7U206, DEF_MYCBO
A1KFQ1, DEF_MYCBPC1AKA5, DEF_MYCBTQ7NAK8, DEF_MYCGA
P47352, DEF_MYCGEA4T2T4, DEF_MYCGIB8ZSF6, DEF_MYCLB
Q9CBI2, DEF_MYCLEB2HQN4, DEF_MYCMMQ73T03, DEF_MYCPA
P75527, DEF_MYCPNQ98PN3, DEF_MYCPUA0QQP8, DEF_MYCS2
A3PTZ4, DEF_MYCSJA1UAD9, DEF_MYCSKQ1BEJ4, DEF_MYCSS
A5TZF5, DEF_MYCTAP9WIJ2, DEF_MYCTOP9WIJ3, DEF_MYCTU
A0PNK2, DEF_MYCUAA1T320, DEF_MYCVPB2A2K1, DEF_NATTJ
B9L6X1, DEF_NAUPAQ5F5P6, DEF_NEIG1A9M464, DEF_NEIM0
P63915, DEF_NEIMAP63916, DEF_NEIMBA1KRE5, DEF_NEIMF
Q2GE16, DEF_NEOSMQ1QH78, DEF_NITHXQ3J6U0, DEF_NITOC
Q2G491, DEF_NOVADQ8ER96, DEF_OCEIHB1ZMD5, DEF_OPITP
A5CF65, DEF_ORITBB3CTU1, DEF_ORITIA6L9R8, DEF_PARD8
Q7U9D4, DEF_PARMWP57948, DEF_PASMUQ6D002, DEF_PECAS
C6DFR5, DEF_PECCPQ03F09, DEF_PEDPAB4SBG6, DEF_PELPB
A5D1C0, DEF_PELTSQ4FNG1, DEF_PELUBB4RDT8, DEF_PHEZH
Q7MYI2, DEF_PHOLLA6L7J9, DEF_PHOV8B1XJP0, DEF_PICP2
B1XSN2, DEF_POLNSB2RMJ1, DEF_PORG3Q7MT07, DEF_PORGI
B4S9B9, DEF_PROA2A2BZN6, DEF_PROM1A2BU25, DEF_PROM5
Q31DB4, DEF_PROM9Q7VED2, DEF_PROMAQ7V3K7, DEF_PROMP
A2BNK7, DEF_PROMSQ46HV9, DEF_PROMTQ9I7A8, DEF_PSEAE
A8F524, DEF_PSELTA4XNB3, DEF_PSEMYQ3IDI2, DEF_PSET1
Q4FVQ4, DEF_PSYA2Q1QET1, DEF_PSYCKA5WBG1, DEF_PSYWF
Q98D52, DEF_RHILOQ92SH6, DEF_RHIMEA5VDM3, DEF_RHIWR
Q7UHZ5, DEF_RHOBAC1B0D9, DEF_RHOOBQ2J2C6, DEF_RHOP2
Q07TX0, DEF_RHOP5Q6NC51, DEF_RHOPAQ21B62, DEF_RHOPB
Q13F18, DEF_RHOPSB3QCH1, DEF_RHOPTA8GMJ8, DEF_RICAH
A8EXV2, DEF_RICCKQ9ZDV8, DEF_RICPRQ68XG1, DEF_RICTY
A7NPM9, DEF_ROSCSA5US58, DEF_ROSS1Q21PV5, DEF_SACD2
B5F7R3, DEF_SALA4A9MN80, DEF_SALARQ57J64, DEF_SALCH
B5FJI2, DEF_SALDCB5R1E3, DEF_SALEPB5RH49, DEF_SALG2
B4TJX7, DEF_SALHSB4SUQ8, DEF_SALNSQ5PIT8, DEF_SALPA
A9N8B1, DEF_SALPBB5BGV3, DEF_SALPKQ2S316, DEF_SALRD
B4TXB0, DEF_SALSVQ8Z1W9, DEF_SALTIQ8ZLM7, DEF_SALTY
A8GKG5, DEF_SERP5B2U2Q4, DEF_SHIB3Q31VZ0, DEF_SHIBS
Q32B63, DEF_SHIDSQ0T016, DEF_SHIF8Q83PZ1, DEF_SHIFL
Q3YWX3, DEF_SHISSQ5WFA2, DEF_SHOC1Q2NQQ4, DEF_SODGM
Q5HGZ3, DEF_STAACP68825, DEF_STAAMP99077, DEF_STAAN
Q6GHZ4, DEF_STAARQ6GAC3, DEF_STAASP68826, DEF_STAAU
Q8NX78, DEF_STAAWQ5HQ78, DEF_STAEQQ8CPN4, DEF_STAES
Q3JZ45, DEF_STRA1Q8E378, DEF_STRA3Q8DXF6, DEF_STRA5
C0M9E1, DEF_STRE4B4U576, DEF_STREMA8AV30, DEF_STRGC
B4SKH7, DEF_STRM5B2FIR4, DEF_STRMKQ8DWC2, DEF_STRMU
P68771, DEF_STRP1Q04JP7, DEF_STRP2P0DC96, DEF_STRP3
B5E5U9, DEF_STRP4Q5X9V1, DEF_STRP6C1C851, DEF_STRP7
Q8NZB7, DEF_STRP8Q1J9R7, DEF_STRPBQ1JJW6, DEF_STRPC
Q1JEV7, DEF_STRPDQ1J4M3, DEF_STRPFA2RGI0, DEF_STRPG
B1ICN7, DEF_STRPIB8ZL02, DEF_STRPJQ48R93, DEF_STRPM
Q9F2F0, DEF_STRPNP0DC97, DEF_STRPQB2IQS1, DEF_STRPS
B5XIL1, DEF_STRPZQ8DP79, DEF_STRR6A4W418, DEF_STRS2
C0MFA6, DEF_STRS7A4VXS1, DEF_STRSYQ5M1R9, DEF_STRT1
Q5M6B0, DEF_STRT2Q03MP6, DEF_STRTDB9DTD6, DEF_STRU0
C1CF38, DEF_STRZJC1CLF5, DEF_STRZPC1CQR2, DEF_STRZT
A4VFH8, DEF_STUS1Q67PR5, DEF_SYMTHA0LEJ7, DEF_SYNFM
A5GQU9, DEF_SYNR3Q0I7A5, DEF_SYNS3Q3AZU8, DEF_SYNS9
Q3AHC4, DEF_SYNSCQ0AXL3, DEF_SYNWWP73441, DEF_SYNY3
C5BKQ0, DEF_TERTTP96113, DEF_THEMAB9K7G9, DEF_THENN
A5ILS1, DEF_THEP1B0KA11, DEF_THEP3B0K292, DEF_THEPX
B9L0C1, DEF_THERPB1LB14, DEF_THESQQ72H33, DEF_THET2
Q5SLH2, DEF_THET8P43522, DEF_THETHQ8DIB4, DEF_THEVB
B5YIL7, DEF_THEYDB8GU11, DEF_THISHC4L7Y4, DEF_TOLAT
O83738, DEF_TREPAB2S3Z6, DEF_TREPSQ83HQ3, DEF_TROW8
Q83GH8, DEF_TROWTB1AJA6, DEF_UREP2Q9PQ25, DEF_UREPA
A7N121, DEF_VIBC1Q8D258, DEF_WIGBRQ73IJ6, DEF_WOLPM
B3CMB1, DEF_WOLPPQ7M7M2, DEF_WOLSUQ5GTG9, DEF_WOLTR
C0R5A2, DEF_WOLWRB2I8S4, DEF_XYLF2P63917, DEF_XYLFA
B0U4M4, DEF_XYLFMP63918, DEF_XYLFTA1JRZ1, DEF_YERE8
A7FNK2, DEF_YERP3Q1C2X9, DEF_YERPAB2K504, DEF_YERPB
Q8ZJ79, DEF_YERPEA9R927, DEF_YERPGQ1CCX6, DEF_YERPN
A4TH23, DEF_YERPPQ664V4, DEF_YERPSB1JJH8, DEF_YERPY
Q9REQ2, DEF_ZYMMO

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-