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ENZYME entry: EC 3.5.1.90

Accepted Name
Adenosylcobinamide hydrolase.
Alternative Name(s)
AdoCbi amidohydrolase.
AdoCbi hydrolase.
Reaction catalysed
Adenosylcobinamide + H(2)O <=> adenosylcobyric acid + (R)-1-aminopropan-2-ol
Comment(s)
  • Involved in the salvage pathway of cobinamide in archaea.
  • Archaea convert adenosylcobinamide (AdoCbi) into adenosylcobinamide phosphate (AdoCbi-P) in two steps.
  • First, the amidohydrolase activity of CbiZ cleaves off the aminopropanol moiety of AdoCbi yielding adenosylcobyric acid (AdoCby); second, AdoCby is converted into AdoCbi-P by the action of EC 6.3.1.10 (CbiB).
Cross-references
BRENDA3.5.1.90
EC2PDB3.5.1.90
ExplorEnz3.5.1.90
PRIAM enzyme-specific profiles3.5.1.90
KEGG Ligand Database for Enzyme Nomenclature3.5.1.90
IUBMB Enzyme Nomenclature3.5.1.90
IntEnz3.5.1.90
MEDLINEFind literature relating to 3.5.1.90
MetaCyc3.5.1.90
Rhea expert-curated reactions3.5.1.90
UniProtKB/Swiss-Prot
Q9HPK9, CBIZ_HALSA;  Q8Q0G3, CBIZ_METMA;  

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