ENZYME entry: EC 3.5.1.99
| Accepted Name |
|---|
| Fatty acid amide hydrolase.
|
| Alternative Name(s) |
|---|
| Anandamide amidohydrolase. |
| Oleamide hydrolase. |
| Reaction catalysed |
|---|
- Anandamide + H(2)O <=> arachidonic acid + ethanolamine
- Oleamide + H(2)O <=> oleic acid + NH(3)
|
| Comment(s) |
|---|
- Integral membrane protein, the enzyme is responsible for the
catabolism of neuromodulatory fatty acid amides, including anandamide
and oleamide, occurs in mammalia.
- Formerly EC 3.5.1.n2.
|
| Cross-references |
|---|
| PROSITE | PDOC00494 |
| BRENDA | 3.5.1.99 |
| EC2PDB | 3.5.1.99 |
| ExplorEnz | 3.5.1.99 |
| PRIAM enzyme-specific profiles | 3.5.1.99 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.1.99 |
| IUBMB Enzyme Nomenclature | 3.5.1.99 |
| IntEnz | 3.5.1.99 |
| MEDLINE | Find literature relating to 3.5.1.99 |
| MetaCyc | 3.5.1.99 |
| UniProtKB/Swiss-Prot |
| Q17449, FAAH1_CAEEL; | O00519, FAAH1_HUMAN; | O08914, FAAH1_MOUSE; |
| Q9TUI8, FAAH1_PIG; | P97612, FAAH1_RAT; | Q6GMR7, FAAH2_HUMAN; |
| Q9U217, FAAH4_CAEEL; | Q7XJJ7, FAAH_ARATH; | Q6DH69, FAH2A_DANRE; |
| Q05AM4, FAH2B_DANRE; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
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