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ENZYME

ENZYME entry: EC 3.5.4.30

Accepted Name
dCTP deaminase (dUMP-forming)
Reaction catalysed
dCTP + 2 H2O <=> diphosphate + dUMP + NH4(+)
Comment(s)
  • Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP, cytosine or deoxycytosine are not deaminated.
  • While most bacteria require two enzymes to form dUMP from dCTP (EC 3.5.4.13 and EC 3.6.1.23), the archaeon Methanocaldococcus jannaschii uses a single enzyme to carry out both functions.
  • This enzyme can also act as a dUTP diphosphatase, but more slowly.
Cross-references
BRENDA3.5.4.30
EC2PDB3.5.4.30
ExplorEnz3.5.4.30
PRIAM enzyme-specific profiles3.5.4.30
KEGG Ligand Database for Enzyme Nomenclature3.5.4.30
IUBMB Enzyme Nomenclature3.5.4.30
IntEnz3.5.4.30
MEDLINEFind literature relating to 3.5.4.30
MetaCyc3.5.4.30
Rhea expert-curated reactions3.5.4.30
UniProtKB/Swiss-Prot
A3DFH7, DCDB_ACET2A0LWS4, DCDB_ACIC1O67539, DCDB_AQUAE
C5C4E1, DCDB_BEUC1B8DUY2, DCDB_BIFA0A1A3S8, DCDB_BIFAA
B3DP64, DCDB_BIFLDQ8G478, DCDB_BIFLOB7GPC4, DCDB_BIFLS
A5CV47, DCDB_CLAM3B0RD07, DCDB_CLASEQ97N13, DCDB_CLOAB
A6M273, DCDB_CLOB8B2UWE6, DCDB_CLOBAB2TNM9, DCDB_CLOBB
B5Y8K7, DCDB_COPPDQ6NEW7, DCDB_CORDIQ8FM44, DCDB_COREF
A4QHN8, DCDB_CORGBQ8NLT9, DCDB_CORGLQ4JXY1, DCDB_CORJK
C4LGU9, DCDB_CORK4Q11TJ6, DCDB_CYTH3B5YB40, DCDB_DICT6
B8DYK8, DCDB_DICTDA8LDU1, DCDB_FRASNQ9KFV3, DCDB_HALH5
B8D0W3, DCDB_HALOHB0R2Y7, DCDB_HALS3Q9HSG3, DCDB_HALSA
Q9ZNJ8, DCDB_HATHIB4U7Y7, DCDB_HYDS0B2GGA3, DCDB_KOCRD
Q6AC71, DCDB_LEIXXB0SH49, DCDB_LEPBAQ04WA6, DCDB_LEPBJ
Q04X69, DCDB_LEPBLB0SQR4, DCDB_LEPBPQ72W72, DCDB_LEPIC
Q8F9W5, DCDB_LEPINA6UWW5, DCDB_META3A7I6N9, DCDB_METB6
Q2FQM7, DCDB_METHJQ57872, DCDB_METJAQ8TYK5, DCDB_METKA
A2SQW1, DCDB_METLZA4FW98, DCDB_METM5A9A9N7, DCDB_METM6
A6VH12, DCDB_METM7A3CTK0, DCDB_METMJQ6LXC6, DCDB_METMP
B8GHN1, DCDB_METPEA5UK79, DCDB_METS3Q2NFH1, DCDB_METST
O27875, DCDB_METTHA6UQ71, DCDB_METVSC5C6P4, DCDB_MICLC
A0QM15, DCDB_MYCA1Q7U297, DCDB_MYCBOA1KFE4, DCDB_MYCBP
C1AJZ9, DCDB_MYCBTA4T0X9, DCDB_MYCGIB8ZTC3, DCDB_MYCLB
Q9CB17, DCDB_MYCLEB2HP20, DCDB_MYCMMQ73T98, DCDB_MYCPA
A0QQ98, DCDB_MYCS2A3PTK2, DCDB_MYCSJA1U9Z8, DCDB_MYCSK
Q1BEY3, DCDB_MYCSSA5TZ48, DCDB_MYCTAP9WP16, DCDB_MYCTO
P9WP17, DCDB_MYCTUA0PLM7, DCDB_MYCUAA1T2M8, DCDB_MYCVP
Q74MA7, DCDB_NANEQQ5YNG0, DCDB_NOCFAA1SQ24, DCDB_NOCSJ
A1RAW1, DCDB_PAEATC0QRW3, DCDB_PERMHB8H717, DCDB_PSECP
A9WT08, DCDB_RENSMC0ZSY9, DCDB_RHOE4Q0S5R4, DCDB_RHOJR
C1AWB6, DCDB_RHOOBA8LWH4, DCDB_SALAIA4X0Z1, DCDB_SALTO
Q82EZ9, DCDB_STRAWQ9X8W0, DCDB_STRCOB1VMF9, DCDB_STRGG
B2V937, DCDB_SULSYQ47KQ7, DCDB_THEFYQ83H71, DCDB_TROW8
Q820X8, DCDB_TROWT

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