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ENZYME entry: EC 3.5.4.35

Accepted Name
tRNA(cytosine(8)) deaminase.
Reaction catalysed
Cytosine(8) in tRNA + H(2)O <=> uracil(8) in tRNA + NH(3)
Comment(s)
  • The enzyme from Methanopyrus kandleri specifically catalyzes the deamimation of cytosine at poition 8 of tRNA in 30 different tRNAs.
  • This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs.
Cross-references
BRENDA3.5.4.35
EC2PDB3.5.4.35
ExplorEnz3.5.4.35
PRIAM enzyme-specific profiles3.5.4.35
KEGG Ligand Database for Enzyme Nomenclature3.5.4.35
IUBMB Enzyme Nomenclature3.5.4.35
IntEnz3.5.4.35
MEDLINEFind literature relating to 3.5.4.35
MetaCyc3.5.4.35
UniProtKB/Swiss-Prot
Q8TWU6, CDAT8_METKA

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