ID   3.5.4.36
DE   mRNA(cytosine(6666)) deaminase.
AN   apolipoprotein B mRNA editing enzyme.
CA   cytidine(6666) in apoB mRNA + H(+) + H2O = NH4(+) + uridine(6666) in apoB
CA   mRNA.
CC   -!- The apolipoprotein B mRNA editing enzyme complex catalyzes the
CC       editing of apolipoprotein B mRNA at cytidine(6666) to uridine,
CC       thereby transforming the codon for glutamine-2153 to a termination
CC       codon.
CC   -!- Editing results in translation of a truncated apolipoprotein B
CC       isoform (apoB-48) with distinct functions in lipid transport.
CC   -!- The catalytic component (APOBEC-1) contains zinc at the active site.
DR   P41238, ABEC1_HUMAN;  Q9EQP0, ABEC1_MESAU;  Q9TUI7, ABEC1_MONDO;
DR   P51908, ABEC1_MOUSE;  Q694B3, ABEC1_PONPY;  P47855, ABEC1_RABIT;
DR   P38483, ABEC1_RAT  ;  Q3SYR3, ABEC2_BOVIN;  Q9Y235, ABEC2_HUMAN;
DR   Q9WV35, ABEC2_MOUSE;  Q694B4, ABEC2_PONPY;
//