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ENZYME

ENZYME entry: EC 3.5.4.37

PURL: https://purl.expasy.org/enzyme/EC/3.5.4.37
Accepted Name
double-stranded RNA adenine deaminase
Alternative Name(s)
double-stranded RNA adenosine deaminase
double-stranded RNA-specific adenosine deaminase
dsRNA adenosine deaminase
Reaction catalysed
adenosine in double-stranded RNA + H2O + H(+) = inosine in double-stranded RNA + NH4(+)
Comment(s)
  • This eukaryotic enzyme is involved in RNA editing.
  • It destabilizes double-stranded RNA through conversion of adenosine to inosine.
  • Inositol hexakisphosphate is required for activity.
Cross-references
BRENDA3.5.4.37
EC2PDB3.5.4.37
ExplorEnz3.5.4.37
KEGG Ligand Database for Enzyme Nomenclature3.5.4.37
IUBMB Enzyme Nomenclature3.5.4.37
MEDLINEFind literature relating to 3.5.4.37
MetaCyc3.5.4.37
Rhea expert-curated reactions3.5.4.37
UniProtKB/Swiss-Prot
Q22618, DSRAD_CAEELP55265, DSRAD_HUMANQ99MU3, DSRAD_MOUSE
P55266, DSRAD_RATP78563, RED1_HUMANQ91ZS8, RED1_MOUSE
P51400, RED1_RAT

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-