ID   3.5.4.38
DE   single-stranded DNA cytosine deaminase.
AN   activation-induced cytidine deaminase.
AN   activation-induced deaminase.
CA   a 2'-deoxycytidine in single-stranded DNA + H(+) + H2O =
CA   a 2'-deoxyuridine in single-stranded DNA + NH4(+).
CC   -!- The enzyme exclusively catalyzes deamination of cytosine in single-
CC       stranded DNA.
CC   -!- It preferentially deaminates five-nucleotide bubbles.
CC   -!- The optimal target consists of a single-stranded NWRCN motif (W =
CC       A or T, R = A or G).
CC   -!- The enzyme initiates antibody diversification processes by
CC       deaminating immunoglobulin sequences.
DR   Q4VDN5, AB3CA_FELCA;  P31941, ABC3A_HUMAN;  Q9UH17, ABC3B_HUMAN;
DR   Q694B5, ABC3C_GORGO;  Q9NRW3, ABC3C_HUMAN;  Q96AK3, ABC3D_HUMAN;
DR   Q8IUX4, ABC3F_HUMAN;  Q7YR25, ABC3G_CHLAE;  Q694C5, ABC3G_ERYPA;
DR   Q694C1, ABC3G_GORGO;  Q9HC16, ABC3G_HUMAN;  Q694B8, ABC3G_LAGLA;
DR   Q694C2, ABC3G_MACFA;  Q7YR23, ABC3G_MACMU;  Q694C4, ABC3G_MACNG;
DR   Q694B6, ABC3G_PANPA;  Q7YR24, ABC3G_PANTR;  Q694B7, ABC3G_PAPAN;
DR   Q694C0, ABC3G_PONPY;  Q694B9, ABC3G_SAGLB;  A9QA56, ABC3H_FELCA;
DR   Q6NTF7, ABC3H_HUMAN;  Q19Q52, ABC3H_MACMU;  Q1WBT4, ABC3H_PONPY;
DR   P60704, ABEC3_CRILO;  Q99J72, ABEC3_MOUSE;  P60705, ABEC3_RAT  ;
DR   Q2PT36, AICDA_BOVIN;  Q75W64, AICDA_CANLF;  Q9GZX7, AICDA_HUMAN;
DR   Q9WVE0, AICDA_MOUSE;
//