Expasy logo

ENZYME

ENZYME entry: EC 3.5.4.43

Accepted Name
hydroxydechloroatrazine ethylaminohydrolase
Alternative Name(s)
2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase
hydroxyatrazine hydrolase
Reaction catalysed
hydroxyatrazine + H2O + H(+) = N-isopropylammelide + ethylamine
Comment(s)
  • This bacterial enzyme is involved in degradation of the herbicide atrazine.
  • The enzyme has a broad substrate range, and requires a monohydroxylated S-triazine ring with a minimum of one primary or secondary amine substituent and either a chloride or amine leaving group.
  • It catalyzes both deamination and dechlorination reactions.
  • Formerly EC 3.5.99.3.
Cross-references
BRENDA3.5.4.43
EC2PDB3.5.4.43
ExplorEnz3.5.4.43
PRIAM enzyme-specific profiles3.5.4.43
KEGG Ligand Database for Enzyme Nomenclature3.5.4.43
IUBMB Enzyme Nomenclature3.5.4.43
IntEnz3.5.4.43
MEDLINEFind literature relating to 3.5.4.43
MetaCyc3.5.4.43
Rhea expert-curated reactions3.5.4.43
UniProtKB/Swiss-Prot
P95442, ATZB_PSESD

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-