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ENZYME

ENZYME entry: EC 3.5.4.5

Accepted Name
cytidine deaminase
Alternative Name(s)
(deoxy)cytidine deaminase
cytidine aminohydrolase
cytosine nucleoside deaminase
Reaction catalysed
  • cytidine + H(+) + H2O = NH4(+) + uridine
  • 2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)
Comment(s)
  • Catalyzes the deamination of cytidine and 2'-deoxycytidine with similar efficiencies.
  • The enzyme, which is widely distributed among organisms, is involved in salvage of both exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  • Formerly EC 3.5.4.14.
Cross-references
BRENDA3.5.4.5
EC2PDB3.5.4.5
ExplorEnz3.5.4.5
PRIAM enzyme-specific profiles3.5.4.5
KEGG Ligand Database for Enzyme Nomenclature3.5.4.5
IUBMB Enzyme Nomenclature3.5.4.5
IntEnz3.5.4.5
MEDLINEFind literature relating to 3.5.4.5
MetaCyc3.5.4.5
Rhea expert-curated reactions3.5.4.5
UniProtKB/Swiss-Prot
O65896, CDA1_ARATHO65571, CDA2_ARATHQ9S847, CDA3_ARATH
Q9S7L8, CDA5_ARATHQ9SU86, CDA6_ARATHQ9SU87, CDA7_ARATH
Q9XEX4, CDA8_ARATHQ5U3U4, CDAC1_DANREQ9BWV3, CDAC1_HUMAN
Q4R683, CDAC1_MACFAQ8BMD5, CDAC1_MOUSEQ5RAX4, CDAC1_PONAB
A3N1Z1, CDD_ACTP2B3GYC3, CDD_ACTP7B0BQT2, CDD_ACTPJ
A6VLF5, CDD_ACTSZA0KJH4, CDD_AERHHA4SNI2, CDD_AERS4
Q5E4R6, CDD_ALIF1B5FEN2, CDD_ALIFMP19079, CDD_BACSU
A8AE87, CDD_CITK8A7MLJ4, CDD_CROS8Q54I82, CDD_DICDI
A7ZNW5, CDD_ECO24B7UFF9, CDD_ECO27B7MF55, CDD_ECO45
B7LA09, CDD_ECO55Q8X648, CDD_ECO57B5YW75, CDD_ECO5E
B7NMA8, CDD_ECO7IB7MXF5, CDD_ECO81B7M4Y8, CDD_ECO8A
C4ZSM3, CDD_ECOBWB1X7N2, CDD_ECODHA8A204, CDD_ECOHS
A1AD04, CDD_ECOK1Q0TFU8, CDD_ECOL5Q8FFV3, CDD_ECOL6
B1IYC6, CDD_ECOLCP0ABF6, CDD_ECOLIB7NCH2, CDD_ECOLU
B6I8J3, CDD_ECOSEB1LKP0, CDD_ECOSMQ1R9T0, CDD_ECOUT
C5BCM4, CDD_EDWI9A4WCI1, CDD_ENT38B2VIF3, CDD_ERWT9
B7LVA3, CDD_ESCF3Q7VMJ6, CDD_HAEDUQ4QK60, CDD_HAEI8
A5UBV9, CDD_HAEIEA5UEI7, CDD_HAEIGP44325, CDD_HAEIN
Q9KD53, CDD_HALH5Q0I4X6, CDD_HISS1B0USP2, CDD_HISS2
P32320, CDD_HUMANB5XP65, CDD_KLEP3A6TBN1, CDD_KLEP7
Q65RG8, CDD_MANSMP56389, CDD_MOUSEP47298, CDD_MYCGE
P47718, CDD_MYCPIP75051, CDD_MYCPNP9WPH2, CDD_MYCTO
P9WPH3, CDD_MYCTUQ9CP11, CDD_PASMUQ6D3B4, CDD_PECAS
C6DDS7, CDD_PECCPQ7N6K3, CDD_PHOLLQ6LRI0, CDD_PHOPR
B4ESY3, CDD_PROMHQ3IBX5, CDD_PSET1B5EYN3, CDD_SALA4
A9MKS5, CDD_SALARQ57MF5, CDD_SALCHB5FMZ9, CDD_SALDC
B5R153, CDD_SALEPB5RC22, CDD_SALG2B4TAK5, CDD_SALHS
B4SY15, CDD_SALNSQ5PE68, CDD_SALPAA9N6L3, CDD_SALPB
C0Q0V4, CDD_SALPCB5BE52, CDD_SALPKB4TNP0, CDD_SALSV
Q8Z5A8, CDD_SALTIQ8ZNM0, CDD_SALTYQ09190, CDD_SCHPO
A8GC32, CDD_SERP5A1S723, CDD_SHEAMB8EF35, CDD_SHEB2
A3D392, CDD_SHEB5A6WLY5, CDD_SHEB8A9KXF0, CDD_SHEB9
Q083S7, CDD_SHEFNB0TQV3, CDD_SHEHHA3QDC9, CDD_SHELP
Q8EDG1, CDD_SHEONA8H5H1, CDD_SHEPAA4Y5R0, CDD_SHEPC
B8CR83, CDD_SHEPWA0KYD1, CDD_SHESAA8FWK2, CDD_SHESH
Q0HHI5, CDD_SHESMQ0HTT9, CDD_SHESRA1RL10, CDD_SHESW
B1KRC5, CDD_SHEWMB2TVV2, CDD_SHIB3Q322V3, CDD_SHIBS
Q32EM3, CDD_SHIDSQ0T2Y0, CDD_SHIF8P0ABF7, CDD_SHIFL
Q3Z062, CDD_SHISSQ2NUD2, CDD_SODGMQ9S3M0, CDD_SPOPS
B7VPF1, CDD_VIBA3A7MVH6, CDD_VIBC1A5F1V7, CDD_VIBC3
Q9KSM5, CDD_VIBCHC3LLS7, CDD_VIBCMQ87Q52, CDD_VIBPA
Q8DA31, CDD_VIBVUQ7MK48, CDD_VIBVYQ06549, CDD_YEAST
A7FJK3, CDD_YERP3Q1C9U7, CDD_YERPAB2JZJ6, CDD_YERPB
Q8ZG08, CDD_YERPEA9R1B9, CDD_YERPGQ1CGT5, CDD_YERPN
A4TKN7, CDD_YERPPQ66C79, CDD_YERPSB1JPZ5, CDD_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
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