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ENZYME

ENZYME entry: EC 3.5.99.11

PURL: https://purl.expasy.org/enzyme/EC/3.5.99.11
Accepted Name
2-aminomuconate deaminase (2-hydroxymuconate-forming)
Reaction catalysed
(2Z,4E)-2-aminomuconate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH4(+)
Comment(s)
  • The enzyme, characterized from the bacterium Comamonas testosteroni CNB-1, converts 2-aminomuconate to 2-hydroxyhexa-2,4-dienedioate, unlike the enzymes from Pseudomonas, which produce (3E)-2-oxohex-3- enedioate (see EC 3.5.99.5).
  • The enzyme also acts on 2-amino-5-chloromuconate.
  • Formerly EC 3.5.1.120.
Cross-references
BRENDA3.5.99.11
EC2PDB3.5.99.11
ExplorEnz3.5.99.11
KEGG Ligand Database for Enzyme Nomenclature3.5.99.11
IUBMB Enzyme Nomenclature3.5.99.11
MEDLINEFind literature relating to 3.5.99.11
MetaCyc3.5.99.11
Rhea expert-curated reactions3.5.99.11
UniProtKB/Swiss-Prot
Q09KQ6, CNBZ_COMTE

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