ID   3.5.99.12
DE   salsolinol synthase.
AN   Sal synthase.
CA   dopamine + acetaldehyde = (R)-salsolinol + H2O.
CC   -!- The enzyme, present in mammalian brains, forms the catechol
CC       isoquinoline (R)-salsolinol.
CC   -!- This compound can be metabolized to (R)-N-methylsalsolinol,
CC       a 1-methyl-4-phenylpyridinium-like neurotoxin that impairs the
CC       function of dopaminergic neurons, causing the clinical symptoms of
CC       Parkinson's disease.
//