ENZYME entry: EC 3.5.99.2
Accepted Name |
Aminopyrimidine aminohydrolase.
|
Alternative Name(s) |
Thiaminase. |
Thiaminase II. |
Reaction catalysed |
- 4-amino-5-aminomethyl-2-methylpyrimidine + H(2)O <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + ammonia
- Thiamine + H(2)O <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole
|
Comment(s) |
Previously known as thiaminase II, this enzyme is involved in the
regeneration of the thiamine pyrimidine from degraded products,
rather than in thiamine degradation, and participates in thiamine
salvage pathways.
|
Cross-references |
BRENDA | 3.5.99.2 |
EC2PDB | 3.5.99.2 |
ExplorEnz | 3.5.99.2 |
PRIAM enzyme-specific profiles | 3.5.99.2 |
KEGG Ligand Database for Enzyme Nomenclature | 3.5.99.2 |
IUBMB Enzyme Nomenclature | 3.5.99.2 |
IntEnz | 3.5.99.2 |
MEDLINE | Find literature relating to 3.5.99.2 |
MetaCyc | 3.5.99.2 |
UniProtKB/Swiss-Prot |
B6TPF2, TENA2_MAIZE; | F4KFT7, TENAC_ARATH; | Q9ASY9, TENAE_ARATH; |
Q9SWB6, TENAE_SOYBN; | Q9K9G8, TENA_BACHD; | P25052, TENA_BACSU; |
A8KRL3, TENA_HELPX; | Q2FF32, TENA_STAA3; | Q2FWG0, TENA_STAA8; |
Q2YUL0, TENA_STAAB; | Q5HEA5, TENA_STAAC; | Q99SG3, TENA_STAAM; |
Q7A4F3, TENA_STAAN; | Q6GEY1, TENA_STAAR; | Q6G7L6, TENA_STAAS; |
Q7A0C8, TENA_STAAW; | O54496, TENA_STACT; | Q5HMC7, TENA_STAEQ; |
Q8CNK1, TENA_STAES; | Q4L7X6, TENA_STAHJ; | Q49Z42, TENA_STAS1; |
|
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UniProtKB/Swiss-Prot entries corresponding to 3.5.99.-
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