ENZYME entry: EC 3.5.99.2
| Accepted Name |
|---|
| aminopyrimidine aminohydrolase.
|
| Alternative Name(s) |
|---|
| thiaminase. |
| thiaminase II. |
| Reaction catalysed |
|---|
- 4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)
- H2O + thiamine <=> 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)
|
| Comment(s) |
|---|
| Previously known as thiaminase II, this enzyme is involved in the
regeneration of the thiamine pyrimidine from degraded products,
rather than in thiamine degradation, and participates in thiamine
salvage pathways.
|
| Cross-references |
|---|
| BRENDA | 3.5.99.2 |
| EC2PDB | 3.5.99.2 |
| ExplorEnz | 3.5.99.2 |
| PRIAM enzyme-specific profiles | 3.5.99.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.99.2 |
| IUBMB Enzyme Nomenclature | 3.5.99.2 |
| IntEnz | 3.5.99.2 |
| MEDLINE | Find literature relating to 3.5.99.2 |
| MetaCyc | 3.5.99.2 |
| Rhea expert-curated reactions | 3.5.99.2 |
| UniProtKB/Swiss-Prot |
| B6TPF2, TENA2_MAIZE; | F4KFT7, TENAC_ARATH; | Q9ASY9, TENAE_ARATH; |
| Q9SWB6, TENAE_SOYBN; | Q9K9G8, TENA_ALKHC; | P25052, TENA_BACSU; |
| A8KRL3, TENA_HELPX; | Q2FF32, TENA_STAA3; | Q2FWG0, TENA_STAA8; |
| Q2YUL0, TENA_STAAB; | Q5HEA5, TENA_STAAC; | Q99SG3, TENA_STAAM; |
| Q7A4F3, TENA_STAAN; | Q6GEY1, TENA_STAAR; | Q6G7L6, TENA_STAAS; |
| Q7A0C8, TENA_STAAW; | O54496, TENA_STACT; | Q5HMC7, TENA_STAEQ; |
| Q8CNK1, TENA_STAES; | Q4L7X6, TENA_STAHJ; | Q49Z42, TENA_STAS1; |
|
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UniProtKB/Swiss-Prot entries corresponding to 3.5.99.-
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