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ENZYME

ENZYME entry: EC 3.6.1.40

PURL: https://purl.expasy.org/enzyme/EC/3.6.1.40
Accepted Name
guanosine-5'-triphosphate,3'-diphosphate diphosphatase
Alternative Name(s)
guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
guanosine pentaphosphate phosphohydrolase
pppGpp 5'-phosphohydrolase
Reaction catalysed
guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate + H(+)
Comment(s)
Also hydrolyzes other guanosine 5'-triphosphate derivatives with at least one unsubstituted phosphate group on the 3'-position, but not GTP, ATP or adenosine 5'-triphosphate,3'-diphosphate.
Cross-references
BRENDA3.6.1.40
EC2PDB3.6.1.40
ExplorEnz3.6.1.40
KEGG Ligand Database for Enzyme Nomenclature3.6.1.40
IUBMB Enzyme Nomenclature3.6.1.40
MEDLINEFind literature relating to 3.6.1.40
MetaCyc3.6.1.40
Rhea expert-curated reactions3.6.1.40
UniProtKB/Swiss-Prot
A0KEG8, GPPA_AERHHA4STJ8, GPPA_AERS4Q5E8U7, GPPA_ALIF1
B5FF86, GPPA_ALIFMA8ACT2, GPPA_CITK8A7MQI3, GPPA_CROS8
A7ZTY0, GPPA_ECO24B7UMN4, GPPA_ECO27B7MGI9, GPPA_ECO45
B7L8C0, GPPA_ECO55Q8XAT5, GPPA_ECO57B5YY27, GPPA_ECO5E
B7NTG3, GPPA_ECO7IB7N272, GPPA_ECO81B7M5C6, GPPA_ECO8A
C4ZZ47, GPPA_ECOBWB1X9Z3, GPPA_ECODHA8A6N3, GPPA_ECOHS
A1AHU9, GPPA_ECOK1Q8FBR0, GPPA_ECOL6B1IWC1, GPPA_ECOLC
P25552, GPPA_ECOLIB7NF84, GPPA_ECOLUB6I4B5, GPPA_ECOSE
B1LLV2, GPPA_ECOSMQ1R4G0, GPPA_ECOUTA4WG31, GPPA_ENT38
B2VG72, GPPA_ERWT9B7LU76, GPPA_ESCF3A6TGG8, GPPA_KLEP7
B5XYZ0, GPPA_KLEV3Q6CZD8, GPPA_PECASC6DHF6, GPPA_PECCP
Q7MYL1, GPPA_PHOLLQ6LLL4, GPPA_PHOPRB4F1V2, GPPA_PROMH
Q15N19, GPPA_PSEA6Q3IDD5, GPPA_PSET1B5EZ39, GPPA_SALA4
A9MJ30, GPPA_SALARQ57HT7, GPPA_SALCHB5FN73, GPPA_SALDC
B5QVH1, GPPA_SALEPB5RFS4, GPPA_SALG2B4TB12, GPPA_SALHS
B4SZ25, GPPA_SALNSQ5PKK4, GPPA_SALPAA9MXF2, GPPA_SALPB
C0Q2V8, GPPA_SALPCB5BIS8, GPPA_SALPKB4TNT2, GPPA_SALSV
P0A268, GPPA_SALTIP0A267, GPPA_SALTYA8G827, GPPA_SERP5
B2TU13, GPPA_SHIB3Q31UK6, GPPA_SHIBSQ329V7, GPPA_SHIDS
Q0SYW9, GPPA_SHIF8Q83PI3, GPPA_SHIFLQ3YVI5, GPPA_SHISS
Q2NQB1, GPPA_SODGMB7VMF0, GPPA_VIBA3A7MXT2, GPPA_VIBC1
A5F3R3, GPPA_VIBC3Q9KV53, GPPA_VIBCHC3LQR0, GPPA_VIBCM
Q87KH4, GPPA_VIBPAQ8DDN5, GPPA_VIBVUQ7MGP6, GPPA_VIBVY
A1JI66, GPPA_YERE8A7FD46, GPPA_YERP3B2K045, GPPA_YERPB
Q74R94, GPPA_YERPEA9R8H6, GPPA_YERPGA4TRC9, GPPA_YERPP
Q66G20, GPPA_YERPSB1JQ12, GPPA_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-