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ENZYME

ENZYME entry: EC 3.6.1.41

Accepted Name
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
Alternative Name(s)
Ap4A hydrolase
diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase
diadenosinetetraphosphatase (symmetrical)
dinucleosidetetraphosphatase (symmetrical)
Reaction catalysed
H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)
Comment(s)
Also acts on bis(5'-guanosyl) tetraphosphate and bis(5'-adenosyl) pentaphosphate, and, more slowly, on some other polyphosphates, forming a nucleoside bisphosphate as one product in all cases (cf. EC 3.6.1.17).
Cross-references
BRENDA3.6.1.41
EC2PDB3.6.1.41
ExplorEnz3.6.1.41
PRIAM enzyme-specific profiles3.6.1.41
KEGG Ligand Database for Enzyme Nomenclature3.6.1.41
IUBMB Enzyme Nomenclature3.6.1.41
IntEnz3.6.1.41
MEDLINEFind literature relating to 3.6.1.41
MetaCyc3.6.1.41
Rhea expert-curated reactions3.6.1.41
UniProtKB/Swiss-Prot
P54456, AP4AH_BACSUQ9KD90, AP4AH_HALH5Q2G297, AP4AH_STAA8
Q8DY32, AP4AH_STRA5B9MFH8, APAH_ACIETA1W551, APAH_ACISJ
A3N0C2, APAH_ACTP2B3GXJ7, APAH_ACTP7B0BP40, APAH_ACTPJ
A6VMA9, APAH_ACTSZA0KGT6, APAH_AERHHA4SR08, APAH_AERS4
O52655, APAH_AGGACQ5E866, APAH_ALIF1B5FGG4, APAH_ALIFM
B6EL47, APAH_ALISLQ0AC59, APAH_ALKEHQ5P6P9, APAH_AROAE
C1DIX1, APAH_AZOVDQ1LSS3, APAH_BAUCHQ7WF80, APAH_BORBR
Q7W3V0, APAH_BORPAA9I1T6, APAH_BORPDQ7W041, APAH_BORPE
B8D8U3, APAH_BUCA5P57242, APAH_BUCAIQ8K9Z9, APAH_BUCAP
B8D747, APAH_BUCATQ89AV3, APAH_BUCBPA3MMA4, APAH_BURM7
A2S9T5, APAH_BURM9Q9AEV8, APAH_BURMAA1V209, APAH_BURMS
A3NYF9, APAH_BURP0Q3JPG7, APAH_BURP1I1WGA2, APAH_BURP2
A3NCP7, APAH_BURP6P0DMK2, APAH_BURPSQ2SYI5, APAH_BURTA
B3PKV6, APAH_CELJUQ1QZ29, APAH_CHRSDQ7NQS0, APAH_CHRVO
A8ALQ2, APAH_CITK8Q47VJ7, APAH_COLP3B6J646, APAH_COXB1
B6J3B1, APAH_COXB2A9KH04, APAH_COXBNA9N9I1, APAH_COXBR
Q83AB7, APAH_COXBUA7MIB2, APAH_CROS8Q478S1, APAH_DECAR
A9BVD2, APAH_DELASA7ZHE2, APAH_ECO24B7UI97, APAH_ECO27
B7MAH4, APAH_ECO45B7L4H2, APAH_ECO55Q8XA15, APAH_ECO57
B5YZ87, APAH_ECO5EB7NHF5, APAH_ECO7IB7MNQ8, APAH_ECO81
B7M0E6, APAH_ECO8AC4ZPX5, APAH_ECOBWB1XC50, APAH_ECODH
A7ZW01, APAH_ECOHSA1A798, APAH_ECOK1Q0TLT8, APAH_ECOL5
Q8FL98, APAH_ECOL6B1IRC7, APAH_ECOLCP05637, APAH_ECOLI
B7N7S4, APAH_ECOLUB6HZ30, APAH_ECOSEB1LFY5, APAH_ECOSM
Q1RGE8, APAH_ECOUTC5B7N9, APAH_EDWI9A4W6F5, APAH_ENT38
B2VGQ8, APAH_ERWT9B7LVU3, APAH_ESCF3B8F4P0, APAH_GLAP5
Q7VLX9, APAH_HAEDUQ4QMZ7, APAH_HAEI8A5U9U1, APAH_HAEIE
A5UH58, APAH_HAEIGP44751, APAH_HAEINC4K4K8, APAH_HAMD5
A4G8L5, APAH_HERARQ0I5C4, APAH_HISS1B0URM8, APAH_HISS2
A6T287, APAH_JANMAP27510, APAH_KLEAEB5Y1Z6, APAH_KLEP3
A6T4I5, APAH_KLEP7Q5X0V3, APAH_LEGPAA5IIB8, APAH_LEGPC
Q5ZRF6, APAH_LEGPHQ5WSM5, APAH_LEGPLQ65UX2, APAH_MANSM
A6VU51, APAH_MARMSQ60CE9, APAH_METCAQ1H450, APAH_METFK
Q5FA03, APAH_NEIG1B4RJQ3, APAH_NEIG2Q9JVF4, APAH_NEIMA
Q82WQ0, APAH_NITEUQ2YCK7, APAH_NITMUQ3JBF6, APAH_NITOC
A1TLA3, APAH_PARC0B2JFC8, APAH_PARP8P57922, APAH_PASMU
Q6D0D8, APAH_PECASC6DEY8, APAH_PECCPQ7N8V9, APAH_PHOLL
Q6LV43, APAH_PHOPRB4F2I4, APAH_PROMHQ48NT9, APAH_PSE14
A6UZ94, APAH_PSEA7B7V4H6, APAH_PSEA8Q02TH3, APAH_PSEAB
Q9I5U7, APAH_PSEAEQ1IG22, APAH_PSEE4Q4K4X3, APAH_PSEF5
C3K329, APAH_PSEFSA4XZJ6, APAH_PSEMYA5VXJ3, APAH_PSEP1
Q3K5T0, APAH_PSEPFB0KJ91, APAH_PSEPGQ88QT8, APAH_PSEPK
B1JE09, APAH_PSEPWQ88A48, APAH_PSESMQ4ZMG3, APAH_PSEU2
A1STS0, APAH_PSYINQ8Y1K9, APAH_RALN1Q21MT2, APAH_SACD2
B5F769, APAH_SALA4A9MQG4, APAH_SALARQ57TH2, APAH_SALCH
B5FI32, APAH_SALDCB5R1S6, APAH_SALEPB5RGC0, APAH_SALG2
B4TJ45, APAH_SALHSB4T6L4, APAH_SALNSQ5PDE1, APAH_SALPA
A9MYM2, APAH_SALPBC0Q5E5, APAH_SALPCB5BL25, APAH_SALPK
B4TWT4, APAH_SALSVP0A1B2, APAH_SALTIP0A1B1, APAH_SALTY
A8G9N8, APAH_SERP5B8EB37, APAH_SHEB2A3D186, APAH_SHEB5
A6WK57, APAH_SHEB8A9L436, APAH_SHEB9Q07YJ6, APAH_SHEFN
A3QBA1, APAH_SHELPQ8EB91, APAH_SHEONA4Y433, APAH_SHEPC
A0L066, APAH_SHESAA8FRV0, APAH_SHESHQ0HLT4, APAH_SHESM
Q0HS04, APAH_SHESRA1RMV0, APAH_SHESWB2U257, APAH_SHIB3
Q326I4, APAH_SHIBSQ32K45, APAH_SHIDSQ0T8E6, APAH_SHIF8
Q83SQ2, APAH_SHIFLQ3Z5W0, APAH_SHISSQ2NVX8, APAH_SODGM
A4VHH8, APAH_STUS1C5BPC0, APAH_TERTTQ3SMC6, APAH_THIDA
B8GMY8, APAH_THISHC4L9L6, APAH_TOLATA7N0G6, APAH_VIBC1
A5F8N0, APAH_VIBC3Q9KUS4, APAH_VIBCHC3LRH2, APAH_VIBCM
Q87ST8, APAH_VIBPAQ8DED0, APAH_VIBVUQ7MP88, APAH_VIBVY
Q8D3I0, APAH_WIGBRQ8PP27, APAH_XANACQ8PCE5, APAH_XANCP
Q3BX84, APAH_XANE5Q2NZI2, APAH_XANOMB2SPT1, APAH_XANOP
Q5GWB7, APAH_XANORB2I5R6, APAH_XYLF2Q9PBJ4, APAH_XYLFA
Q87C83, APAH_XYLFTA1JJF2, APAH_YERE8A7FMC3, APAH_YERP3
Q1C0H7, APAH_YERPAB2K485, APAH_YERPBQ8ZIK7, APAH_YERPE
A9QZZ2, APAH_YERPGQ1CMT4, APAH_YERPNA4TQE0, APAH_YERPP
Q66ER0, APAH_YERPSB1JKY5, APAH_YERPYP47482, NNAAH_MYCGE
P75442, NNAAH_MYCPNQ9PQ21, NNAAH_UREPA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-