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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.6.1.54

Accepted Name
UDP-2,3-diacylglucosamine diphosphatase.
Alternative Name(s)
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine diphosphatase.
UDP-2,3-diacylglucosamine hydrolase.
UDP-2,3-diacylglucosamine pyrophosphatase.
Reaction catalysed
UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + H(2)O <=> 2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate + UMP
Comment(s)
  • The enzyme catalyzes a step in the biosynthesis of lipid A.
  • Formerly EC 3.6.1.n5.
Cross-references
BRENDA3.6.1.54
EC2PDB3.6.1.54
ExplorEnz3.6.1.54
PRIAM enzyme-specific profiles3.6.1.54
KEGG Ligand Database for Enzyme Nomenclature3.6.1.54
IUBMB Enzyme Nomenclature3.6.1.54
IntEnz3.6.1.54
MEDLINEFind literature relating to 3.6.1.54
MetaCyc3.6.1.54
UniProtKB/Swiss-Prot
A6VR19, LPXH_ACTSZ;  A0KLW6, LPXH_AERHH;  A4SLC4, LPXH_AERS4;  
Q5E4E9, LPXH_ALIF1;  B5FF31, LPXH_ALIFM;  B6EH41, LPXH_ALISL;  
Q5P1I2, LPXH_AROAE;  C1DHE3, LPXH_AZOVD;  Q7VRB5, LPXH_BLOFL;  
Q493A2, LPXH_BLOPB;  Q7WLL3, LPXH_BORBR;  Q7W865, LPXH_BORPA;  
Q7VX99, LPXH_BORPE;  B3PHJ5, LPXH_CELJU;  Q1QVV3, LPXH_CHRSD;  
Q7NT75, LPXH_CHRVO;  B6IZ08, LPXH_COXB2;  A9KBJ4, LPXH_COXBN;  
A9N926, LPXH_COXBR;  Q83BL5, LPXH_COXBU;  A7MJY7, LPXH_CROS8;  
A7ZIT3, LPXH_ECO24;  B7UKK1, LPXH_ECO27;  B7ME47, LPXH_ECO45;  
B7L7F1, LPXH_ECO55;  Q8XCU1, LPXH_ECO57;  B5YPN9, LPXH_ECO5E;  
B7NL16, LPXH_ECO7I;  B7MRI7, LPXH_ECO81;  B7M4M7, LPXH_ECO8A;  
C4ZUX2, LPXH_ECOBW;  B1XGC2, LPXH_ECODH;  A7ZXH9, LPXH_ECOHS;  
A1A8J0, LPXH_ECOK1;  Q0TKB7, LPXH_ECOL5;  Q8FK47, LPXH_ECOL6;  
B1IZ77, LPXH_ECOLC;  P43341, LPXH_ECOLI;  B7N978, LPXH_ECOLU;  
B6I0G9, LPXH_ECOSE;  B1LKE3, LPXH_ECOSM;  Q1RF10, LPXH_ECOUT;  
C5B8V8, LPXH_EDWI9;  A4W7I2, LPXH_ENT38;  B7LJI2, LPXH_ESCF3;  
Q7VKH0, LPXH_HAEDU;  Q4QMG1, LPXH_HAEI8;  A5UDZ1, LPXH_HAEIE;  
A5UHN7, LPXH_HAEIG;  P44046, LPXH_HAEIN;  Q0I254, LPXH_HAES1;  
Q2SK43, LPXH_HAHCH;  C4K6H0, LPXH_HAMD5;  B0UVZ2, LPXH_HISS2;  
B5Y0K8, LPXH_KLEP3;  A6T5R0, LPXH_KLEP7;  C1D6W3, LPXH_LARHH;  
Q65V94, LPXH_MANSM;  A1U1R0, LPXH_MARHV;  Q5F6U7, LPXH_NEIG1;  
A9M211, LPXH_NEIM0;  Q9JVS0, LPXH_NEIMA;  Q9K0P2, LPXH_NEIMB;  
A1KSF3, LPXH_NEIMF;  Q3J8Y6, LPXH_NITOC;  Q9CPE3, LPXH_PASMU;  
Q6D2E1, LPXH_PECAS;  C6DAX5, LPXH_PECCP;  Q7N0S3, LPXH_PHOLL;  
Q6LT69, LPXH_PHOPR;  B4F1M8, LPXH_PROMH;  Q48L09, LPXH_PSE14;  
A6V730, LPXH_PSEA7;  B7VB87, LPXH_PSEA8;  Q02KT3, LPXH_PSEAB;  
Q9I2V0, LPXH_PSEAE;  Q1IBQ2, LPXH_PSEE4;  Q4K9R8, LPXH_PSEF5;  
C3JYD6, LPXH_PSEFS;  A4XVG4, LPXH_PSEMY;  A5W461, LPXH_PSEP1;  
Q3KA25, LPXH_PSEPF;  B0KUU3, LPXH_PSEPG;  Q88IU7, LPXH_PSEPK;  
B1J842, LPXH_PSEPW;  Q87YP9, LPXH_PSESM;  Q4ZVP2, LPXH_PSEU2;  
A4VL70, LPXH_PSEU5;  A1SWR2, LPXH_PSYIN;  Q8Y081, LPXH_RALSO;  
B5EYD5, LPXH_SALA4;  A9MLB0, LPXH_SALAR;  Q57S31, LPXH_SALCH;  
B5FLP5, LPXH_SALDC;  B5QUU8, LPXH_SALEP;  B5R6W8, LPXH_SALG2;  
B4T9M8, LPXH_SALHS;  B4SXP0, LPXH_SALNS;  Q5PCF3, LPXH_SALPA;  
A9MW33, LPXH_SALPB;  C0PVI6, LPXH_SALPC;  B5BD00, LPXH_SALPK;  
B4TN57, LPXH_SALSV;  Q8Z8P7, LPXH_SALTI;  Q8ZR69, LPXH_SALTY;  
A8GAX8, LPXH_SERP5;  A1S4X0, LPXH_SHEAM;  B8E5F4, LPXH_SHEB2;  
A3D300, LPXH_SHEB5;  A6WLP6, LPXH_SHEB8;  A9KWH2, LPXH_SHEB9;  
Q07ZX3, LPXH_SHEFN;  B0TLV4, LPXH_SHEHH;  A3QFY1, LPXH_SHELP;  
Q8EG24, LPXH_SHEON;  A8H619, LPXH_SHEPA;  A4Y5H7, LPXH_SHEPC;  
B8CRG2, LPXH_SHEPW;  A0KYM4, LPXH_SHESA;  Q0HH96, LPXH_SHESM;  
Q0HTK2, LPXH_SHESR;  A1RL94, LPXH_SHESW;  B2TTB5, LPXH_SHIB3;  
Q324Y1, LPXH_SHIBS;  Q32JL2, LPXH_SHIDS;  Q0T778, LPXH_SHIF8;  
Q83M28, LPXH_SHIFL;  Q3Z4P3, LPXH_SHISS;  Q2NV47, LPXH_SODGM;  
B4SLL1, LPXH_STRM5;  B2FQP4, LPXH_STRMK;  C4LG06, LPXH_TOLAT;  
A5F743, LPXH_VIBC3;  Q9KQZ7, LPXH_VIBCH;  C3LNF3, LPXH_VIBCM;  
Q87QK1, LPXH_VIBPA;  B7VGZ3, LPXH_VIBTL;  Q8D8Q9, LPXH_VIBVU;  
Q7MLR7, LPXH_VIBVY;  Q8D2V8, LPXH_WIGBR;  P58975, LPXH_XANAC;  
Q4URK1, LPXH_XANC8;  B0RU17, LPXH_XANCB;  P58976, LPXH_XANCP;  
Q2NZQ3, LPXH_XANOM;  B2SMK4, LPXH_XANOP;  Q5GWJ5, LPXH_XANOR;  
B2I9U7, LPXH_XYLF2;  Q9PAD0, LPXH_XYLFA;  B0U5J4, LPXH_XYLFM;  
Q87A66, LPXH_XYLFT;  A1JNQ2, LPXH_YERE8;  A7FL48, LPXH_YERP3;  
Q1C4T9, LPXH_YERPA;  B2K7N0, LPXH_YERPB;  Q8ZCB8, LPXH_YERPE;  
A9R251, LPXH_YERPG;  Q1CKY3, LPXH_YERPN;  A4TP65, LPXH_YERPP;  
Q66DL1, LPXH_YERPS;  B1JHJ3, LPXH_YERPY;  Q9A716, LPXI_CAUVC;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-