ID   3.6.1.59
DE   5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase.
AN   m(7)GpppN m(7)GMP phosphohydrolase.
AN   m(7)GpppX diphosphatase.
AN   m(7)GpppX pyrophosphatase.
CA   a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA +
CA   H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-
CA   GMP.
CC   -!- The enzyme removes (decaps) the N(7)-methylguanosine 5-phosphate cap
CC       from an mRNA degraded to a maximal length of 10 nucleotides.
CC   -!- Decapping is an important process in the control of eukaryotic mRNA
CC       degradation.
CC   -!- The enzyme functions to clear the cell of cap structure following
CC       decay of the RNA body.
CC   -!- The nematode enzyme can also decap triply methylated substrates,
CC       5'-(N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-[mRNA].
CC   -!- Formerly EC 3.6.1.30.
DR   D3K0N9, DCPS_ASCSU ;  Q8MJJ7, DCPS_BOVIN ;  G5EFS4, DCPS_CAEEL ;
DR   Q96C86, DCPS_HUMAN ;  Q9DAR7, DCPS_MOUSE ;  Q8MIZ3, DCPS_PIG   ;
DR   Q8K4F7, DCPS_RAT   ;  Q9P7C9, DCPS_SCHPO ;  Q06151, DCPS_YEAST ;
DR   A2VE79, NUDT3_BOVIN;  O95989, NUDT3_HUMAN;  Q9JI46, NUDT3_MOUSE;
DR   Q566C7, NUDT3_RAT  ;
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