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ENZYME

ENZYME entry: EC 3.6.1.66

Accepted Name
XTP/dITP diphosphatase
Alternative Name(s)
hypoxanthine/xanthine dNTP pyrophosphatase
Reaction catalysed
  • H2O + XTP <=> diphosphate + H(+) + XMP
  • dITP + H2O <=> dIMP + diphosphate + H(+)
  • H2O + ITP <=> diphosphate + H(+) + IMP
Comment(s)
The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP, dITP and ITP.
Cross-references
BRENDA3.6.1.66
EC2PDB3.6.1.66
ExplorEnz3.6.1.66
PRIAM enzyme-specific profiles3.6.1.66
KEGG Ligand Database for Enzyme Nomenclature3.6.1.66
IUBMB Enzyme Nomenclature3.6.1.66
IntEnz3.6.1.66
MEDLINEFind literature relating to 3.6.1.66
MetaCyc3.6.1.66
Rhea expert-curated reactions3.6.1.66
UniProtKB/Swiss-Prot
A9NGK2, IXTPA_ACHLIA1TT41, IXTPA_ACIACQ6FEQ6, IXTPA_ACIAD
B7H0A1, IXTPA_ACIB3B7I4X1, IXTPA_ACIB5B2I3B3, IXTPA_ACIBC
A3M1X9, IXTPA_ACIBTC1F8I0, IXTPA_ACIC5B9MEJ9, IXTPA_ACIET
A1W4I7, IXTPA_ACISJQ8UIG9, IXTPA_AGRFCQ21XZ3, IXTPA_ALBFT
A8ESC9, IXTPA_ALIB4Q5WEM4, IXTPA_ALKCKQ2IEX2, IXTPA_ANADE
A7HFW2, IXTPA_ANADFO66580, IXTPA_AQUAEO28046, IXTPA_ARCFU
Q5P5J5, IXTPA_AROAEQ81LB0, IXTPA_BACANQ72ZT2, IXTPA_BACC1
Q817P4, IXTPA_BACCRQ633V5, IXTPA_BACCZQ64MG2, IXTPA_BACFR
Q6HD43, IXTPA_BACHKQ65GG3, IXTPA_BACLDP94558, IXTPA_BACSU
Q8A327, IXTPA_BACTNQ6G565, IXTPA_BARHEQ6G1E6, IXTPA_BARQU
Q6MJR8, IXTPA_BDEBAB8DVS6, IXTPA_BIFA0B3DTK7, IXTPA_BIFLD
Q8G7I1, IXTPA_BIFLOB7GN27, IXTPA_BIFLSQ0SNR4, IXTPA_BORAP
Q7WI95, IXTPA_BORBRO51263, IXTPA_BORBUB7J1H5, IXTPA_BORBZ
B5RL72, IXTPA_BORDLQ662B8, IXTPA_BORGPQ7W6C6, IXTPA_BORPA
Q7VXX8, IXTPA_BORPEB5RR63, IXTPA_BORRAQ89WK5, IXTPA_BRADU
A5E8I8, IXTPA_BRASBP64305, IXTPA_BRUMEP64306, IXTPA_BRUSU
Q62HZ7, IXTPA_BURMAQ63RV4, IXTPA_BURPSQ8RC29, IXTPA_CALS4
A7ZBP3, IXTPA_CAMC1A0RMP5, IXTPA_CAMFFA7HZE0, IXTPA_CAMHC
A8FN54, IXTPA_CAMJ8A7H1W5, IXTPA_CAMJDQ9PMS6, IXTPA_CAMJE
A1W0Z2, IXTPA_CAMJJQ5HT36, IXTPA_CAMJRQ9ABS4, IXTPA_CAUVC
Q5L4Q6, IXTPA_CHLABQ821F9, IXTPA_CHLCVQ256I5, IXTPA_CHLFF
Q9PJD4, IXTPA_CHLMUQ9Z7D1, IXTPA_CHLPNB0B8I0, IXTPA_CHLT2
Q3KL90, IXTPA_CHLTAB0BA59, IXTPA_CHLTBQ8KFJ6, IXTPA_CHLTE
O84611, IXTPA_CHLTRQ7NZJ6, IXTPA_CHRVOQ97FR2, IXTPA_CLOAB
Q8XI68, IXTPA_CLOPEQ891I4, IXTPA_CLOTEQ6NFN7, IXTPA_CORDI
Q8FMU9, IXTPA_COREFA4QGQ5, IXTPA_CORGBQ8NMR5, IXTPA_CORGL
Q4JX01, IXTPA_CORJKB1VGW8, IXTPA_CORU7Q83FA3, IXTPA_COXBU
Q6A760, IXTPA_CUTAKC1CXX6, IXTPA_DEIDVQ1IW81, IXTPA_DEIGD
Q9RXX6, IXTPA_DEIRAA9BTA7, IXTPA_DELASQ6AQD7, IXTPA_DESPS
A4J7Y6, IXTPA_DESRMQ726F4, IXTPA_DESVHB5YEU3, IXTPA_DICT6
Q8XCU5, IXTPA_ECO57Q8FE27, IXTPA_ECOL6P52061, IXTPA_ECOLI
B2KEA9, IXTPA_ELUMPB2VEZ3, IXTPA_ERWT9B1YJW5, IXTPA_EXIS2
C4L4I7, IXTPA_EXISAA5FH89, IXTPA_FLAJ1A6H0L2, IXTPA_FLAPJ
Q0RQL6, IXTPA_FRAAAQ5NEQ9, IXTPA_FRATTQ5KWI6, IXTPA_GEOKA
Q74C80, IXTPA_GEOSLQ7NN81, IXTPA_GLOVIQ5FRF4, IXTPA_GLUOX
A0M0C9, IXTPA_GRAFKQ7VLS3, IXTPA_HAEDUP44598, IXTPA_HAEIN
Q9K8D9, IXTPA_HALH5A1WVN6, IXTPA_HALHLQ7VF43, IXTPA_HELHP
B4U8R9, IXTPA_HYDS0A2BJY7, IXTPA_HYPBUQ5QY51, IXTPA_IDILO
A8A8W1, IXTPA_IGNH4B1L6T7, IXTPA_KORCOQ5FLV7, IXTPA_LACAC
Q74KU4, IXTPA_LACJOQ9CG29, IXTPA_LACLAQ88V20, IXTPA_LACPL
Q5X245, IXTPA_LEGPAQ5ZSN3, IXTPA_LEGPHQ5WTW9, IXTPA_LEGPL
Q6AEL0, IXTPA_LEIXXB0SE38, IXTPA_LEPBAB1Y0J8, IXTPA_LEPCP
Q72UV8, IXTPA_LEPICQ8F031, IXTPA_LEPINQ03YJ8, IXTPA_LEUMM
Q92CH0, IXTPA_LISINQ720J0, IXTPA_LISMFQ8Y7N5, IXTPA_LISMO
Q8EVN6, IXTPA_MALP2Q65RQ6, IXTPA_MANSMQ8TJS1, IXTPA_METAC
Q602P0, IXTPA_METCAB3DV19, IXTPA_METI4Q57679, IXTPA_METJA
Q8TV07, IXTPA_METKAQ8PZ91, IXTPA_METMAA2SJB9, IXTPA_METPP
D9PYS9, IXTPA_METTMB1MLZ4, IXTPA_MYCA9P64308, IXTPA_MYCBO
P52063, IXTPA_MYCLEQ6MT00, IXTPA_MYCMSQ73X89, IXTPA_MYCPA
P9WMR6, IXTPA_MYCTOP9WMR7, IXTPA_MYCTUB2A6I7, IXTPA_NATTJ
B9L638, IXTPA_NAUPAQ9JVG5, IXTPA_NEIMAQ9K0G6, IXTPA_NEIMB
Q82XJ3, IXTPA_NITEUA6Q5H7, IXTPA_NITSBQ5Z0V0, IXTPA_NOCFA
Q8YM52, IXTPA_NOSS1Q8EPJ6, IXTPA_OCEIHB1ZXD5, IXTPA_OPITP
A6LGA4, IXTPA_PARD8Q7U9M0, IXTPA_PARMWQ6MF40, IXTPA_PARUW
Q9CKF5, IXTPA_PASMUQ6D117, IXTPA_PECASQ7N7H2, IXTPA_PHOLL
Q6LML4, IXTPA_PHOPRQ6L1H9, IXTPA_PICTOA1VKF6, IXTPA_POLNA
Q7MUC6, IXTPA_PORGIA2C0B3, IXTPA_PROM1Q7VDQ7, IXTPA_PROMA
Q7V4S3, IXTPA_PROMMQ7V316, IXTPA_PROMPQ46H95, IXTPA_PROMT
Q9I6A8, IXTPA_PSEAEQ88CT0, IXTPA_PSEPKQ87V88, IXTPA_PSESM
Q8ZVB5, IXTPA_PYRAEQ8U446, IXTPA_PYRFUO59580, IXTPA_PYRHO
Q8XXF4, IXTPA_RALSOQ98DN4, IXTPA_RHILOQ92SK4, IXTPA_RHIME
Q7UGM3, IXTPA_RHOBAB6IVK5, IXTPA_RHOCSQ6NCY9, IXTPA_RHOPA
Q2RN61, IXTPA_RHORTQ5LWF7, IXTPA_RUEPOQ97ZZ0, IXTPA_SACS2
Q5PMK9, IXTPA_SALPAQ8Z3U6, IXTPA_SALTIQ8ZM45, IXTPA_SALTY
Q8EBY7, IXTPA_SHEONQ83JS0, IXTPA_SHIFLQ5HGT2, IXTPA_STAAC
P64309, IXTPA_STAAMP99094, IXTPA_STAANQ6GHT4, IXTPA_STAAR
Q6GA63, IXTPA_STAASP58995, IXTPA_STAAWQ5HQ23, IXTPA_STAEQ
Q8CSY5, IXTPA_STAESQ8E3V8, IXTPA_STRA3Q8DY93, IXTPA_STRA5
Q82D15, IXTPA_STRAWQ9S2H9, IXTPA_STRCOQ8DSQ6, IXTPA_STRMU
Q9A1B6, IXTPA_STRP1P0DB58, IXTPA_STRP3Q5XDP8, IXTPA_STRP6
Q8P2D2, IXTPA_STRP8P64310, IXTPA_STRPNP0DB59, IXTPA_STRPQ
P64311, IXTPA_STRR6Q5M1I4, IXTPA_STRT1Q5M626, IXTPA_STRT2
Q30UH9, IXTPA_SULDNA6Q6L9, IXTPA_SULNBB2V8P5, IXTPA_SULSY
Q67SL4, IXTPA_SYMTHQ3A2Y7, IXTPA_SYNC1A0LG38, IXTPA_SYNFM
Q0IDG4, IXTPA_SYNS3P74432, IXTPA_SYNY3Q9HLA4, IXTPA_THEAC
Q5JEX8, IXTPA_THEKOQ9WY06, IXTPA_THEMAA5IKR2, IXTPA_THEP1
B0KBM4, IXTPA_THEP3B0K3T5, IXTPA_THEPXQ72I42, IXTPA_THET2
Q5SHS6, IXTPA_THET8Q8DHZ6, IXTPA_THEVBB5YHP2, IXTPA_THEYD
B8GPB3, IXTPA_THISHQ73KE7, IXTPA_TREDEO83452, IXTPA_TREPA
B2S334, IXTPA_TREPSQ83HF7, IXTPA_TROW8Q83FT2, IXTPA_TROWT
A1WQF4, IXTPA_VEREIQ9KUQ9, IXTPA_VIBCHQ87LJ1, IXTPA_VIBPA
Q8DCB9, IXTPA_VIBVUQ7MHJ0, IXTPA_VIBVYQ8D3C3, IXTPA_WIGBR
Q7MR19, IXTPA_WOLSUQ8PH61, IXTPA_XANACQ4UY37, IXTPA_XANC8
Q8P5T3, IXTPA_XANCPQ5H3S6, IXTPA_XANORQ9PD73, IXTPA_XYLFA
Q87DG2, IXTPA_XYLFTQ8ZHF4, IXTPA_YERPEQ666N1, IXTPA_YERPS
Q5NRL7, IXTPA_ZYMMO

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-