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ENZYME

ENZYME entry: EC 3.6.1.73

PURL: https://purl.expasy.org/enzyme/EC/3.6.1.73
Accepted Name
inosine/xanthosine triphosphatase
Reaction catalysed
  • ITP + H2O = IDP + phosphate + H(+)
  • XTP + H2O = XDP + phosphate + H(+)
Comment(s)
  • The enzyme, characterized from the bacterium Escherichia coli, preferentially hydrolyzes inosine triphosphate and xanthosine triphosphate, which are formed by oxidative deamination damage.
  • By hydrolyzing these damaged nucleotides, the enzyme prevents their incorporation into RNA.
Cross-references
BRENDA3.6.1.73
EC2PDB3.6.1.73
ExplorEnz3.6.1.73
KEGG Ligand Database for Enzyme Nomenclature3.6.1.73
IUBMB Enzyme Nomenclature3.6.1.73
MEDLINEFind literature relating to 3.6.1.73
MetaCyc3.6.1.73
Rhea expert-curated reactions3.6.1.73
UniProtKB/Swiss-Prot
Q9HIY2, COPP_THEACQ97BQ0, COPP_THEVOQ9YDY1, NCPP_AERPE
Q5E7E1, NCPP_ALIF1B5FAQ4, NCPP_ALIFMO29361, NCPP_ARCFU
A8MA42, NCPP_CALMQA8ALW2, NCPP_CITK8A7MIJ1, NCPP_CROS8
B7UR24, NCPP_ECO27B7MNK3, NCPP_ECO45B7LEP0, NCPP_ECO55
Q8XB14, NCPP_ECO57C4ZT76, NCPP_ECOBWB1XFK4, NCPP_ECODH
Q8FA41, NCPP_ECOL6B1IS25, NCPP_ECOLCP39411, NCPP_ECOLI
B6I6P2, NCPP_ECOSEA4W6B2, NCPP_ENT38P39431, NCPP_ENTCL
B2VH10, NCPP_ERWT9Q9K7V3, NCPP_HALH5P39430, NCPP_KLEAE
A6TI08, NCPP_KLEP7B5Y265, NCPP_KLEV3B1L5W9, NCPP_KORCO
Q0W5C7, NCPP_METARQ57709, NCPP_METJAQ8TV89, NCPP_METKA
O27919, NCPP_METTHQ8EP79, NCPP_OCEIHQ6D0A1, NCPP_PECAS
C6DF26, NCPP_PECCPQ7N901, NCPP_PHOLLQ6LUG1, NCPP_PHOPR
B4EY51, NCPP_PROMHQ8ZUF6, NCPP_PYRAEA4WJ90, NCPP_PYRAR
A3MVS2, NCPP_PYRCJA1RUC0, NCPP_PYRILB1YBH2, NCPP_PYRNV
C3NJ80, NCPP_SACI1C3MJC4, NCPP_SACI2C3N0B6, NCPP_SACI3
C3MTQ6, NCPP_SACI4C4KJG4, NCPP_SACI6C3N7X4, NCPP_SACI7
Q97WI6, NCPP_SACS2B5F542, NCPP_SALA4A9MR95, NCPP_SALAR
Q57G27, NCPP_SALCHB5FTD8, NCPP_SALDCB5R3B6, NCPP_SALEP
B5R9W2, NCPP_SALG2B4TH17, NCPP_SALHSB4T4I8, NCPP_SALNS
Q5PK30, NCPP_SALPAA9N7F4, NCPP_SALPBC0Q8F4, NCPP_SALPC
B5BAL0, NCPP_SALPKB4TU54, NCPP_SALSVP39432, NCPP_SALTY
A8G9J3, NCPP_SERP5A6WS92, NCPP_SHEB8A9L1P1, NCPP_SHEB9
Q8EIC6, NCPP_SHEONA0L0M2, NCPP_SHESAQ0HM78, NCPP_SHESM
Q0HRK8, NCPP_SHESRQ96YP8, NCPP_SULTOQ5JJ32, NCPP_THEKO
Q9KU27, NCPP_VIBCHC3LSV6, NCPP_VIBCMQ87S70, NCPP_VIBPA
Q8DEU6, NCPP_VIBVUQ7MNK7, NCPP_VIBVYA1JJB7, NCPP_YERE8
A7FMF9, NCPP_YERP3Q1C0L6, NCPP_YERPAB2K3K4, NCPP_YERPB
Q8ZIP1, NCPP_YERPEA9R033, NCPP_YERPGQ1CMX3, NCPP_YERPN
A4TQH6, NCPP_YERPPQ66EU4, NCPP_YERPSB1JL21, NCPP_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-