ID   3.6.5.2
DE   small monomeric GTPase.
CA   GTP + H2O = GDP + H(+) + phosphate.
CC   -!- A family of about 50 enzymes with a molecular mass of 21 kDa that are
CC       distantly related to the alpha-subunit of EC 3.6.1.46.
CC   -!- Involved in cell-growth regulation (Ras subfamily), membrane vesicle
CC       traffic and uncoating (Rab and ARF subfamilies), nuclear protein
CC       import (Ran subfamily) and organization of the cytoskeleton (Rho and
CC       Rac subfamilies).
CC   -!- Formerly EC 3.6.1.47.
DR   Q94231, ARF11_CAEEL;  Q61LA8, ARF12_CAEBR;  Q10943, ARF12_CAEEL;
DR   P36397, ARF1_ARATH ;  P84080, ARF1_BOVIN ;  Q96361, ARF1_BRARP ;
DR   O23778, ARF1_CATRO ;  P51821, ARF1_CHLRE ;  P51822, ARF1_DAUCA ;
DR   O00909, ARF1_DICDI ;  P61209, ARF1_DROME ;  P84077, ARF1_HUMAN ;
DR   P61210, ARF1_LOCMI ;  Q4R5P2, ARF1_MACFA ;  P84078, ARF1_MOUSE ;
DR   Q06396, ARF1_ORYSJ ;  Q7KQL3, ARF1_PLAF7 ;  Q94650, ARF1_PLAFA ;
DR   Q25761, ARF1_PLAFO ;  P84079, ARF1_RAT   ;  O48649, ARF1_SALBA ;
DR   P36579, ARF1_SCHPO ;  P51824, ARF1_SOLTU ;  P51643, ARF1_XENLA ;
DR   P11076, ARF1_YEAST ;  P26990, ARF6_CHICK ;  P62330, ARF6_HUMAN ;
DR   P62331, ARF6_MOUSE ;  Q007T5, ARF6_PIG   ;  P62332, ARF6_RAT   ;
DR   P51645, ARF6_XENLA ;  Q2KI07, ARL8B_BOVIN;  Q9NVJ2, ARL8B_HUMAN;
DR   Q4R4S4, ARL8B_MACFA;  Q9CQW2, ARL8B_MOUSE;  Q5R6E7, ARL8B_PONAB;
DR   Q66HA6, ARL8B_RAT  ;  Q2KJ93, CDC42_BOVIN;  P60952, CDC42_CANLF;
DR   Q90694, CDC42_CHICK;  P40793, CDC42_DROME;  Q29HY3, CDC42_DROPS;
DR   P60953, CDC42_HUMAN;  Q4R4R6, CDC42_MACFA;  P60766, CDC42_MOUSE;
DR   Q007T2, CDC42_PIG  ;  Q8CFN2, CDC42_RAT  ;  P19073, CDC42_YEAST;
DR   Q94CF0, EHD1_ARATH ;  B3LF48, EHD2_ARATH ;  Q94148, RAB10_CAEEL;
DR   P24409, RAB10_CANLF;  Q5ZIT5, RAB10_CHICK;  P61026, RAB10_HUMAN;
DR   P61027, RAB10_MOUSE;  Q5R5U1, RAB10_PONAB;  P35281, RAB10_RAT  ;
DR   P62822, RAB1A_CANLF;  P62820, RAB1A_HUMAN;  P62821, RAB1A_MOUSE;
DR   Q52NJ2, RAB1A_PIG  ;  Q6NYB7, RAB1A_RAT  ;  Q2HJH2, RAB1B_BOVIN;
DR   Q9H0U4, RAB1B_HUMAN;  Q4R8X3, RAB1B_MACFA;  Q9D1G1, RAB1B_MOUSE;
DR   Q06AU7, RAB1B_PIG  ;  Q5RE13, RAB1B_PONAB;  P10536, RAB1B_RAT  ;
DR   Q92928, RAB1C_HUMAN;  P61105, RAB2A_CANLF;  Q90965, RAB2A_CHICK;
DR   P36409, RAB2A_DICDI;  P61019, RAB2A_HUMAN;  Q4R4X6, RAB2A_MACFA;
DR   P86207, RAB2A_MESAU;  P53994, RAB2A_MOUSE;  Q5R6B6, RAB2A_PONAB;
DR   Q01971, RAB2A_RABIT;  P05712, RAB2A_RAT  ;  Q8WUD1, RAB2B_HUMAN;
DR   P59279, RAB2B_MOUSE;  O18333, RAB2_DROME ;  Q2TBH7, RAB4A_BOVIN;
DR   Q6PHI9, RAB4A_DANRE;  P20338, RAB4A_HUMAN;  P56371, RAB4A_MOUSE;
DR   P05714, RAB4A_RAT  ;  P61017, RAB4B_CANLF;  Q68EK7, RAB4B_DANRE;
DR   P61018, RAB4B_HUMAN;  Q91ZR1, RAB4B_MOUSE;  P51146, RAB4B_RAT  ;
DR   Q0IIG7, RAB5A_BOVIN;  P18066, RAB5A_CANLF;  P20339, RAB5A_HUMAN;
DR   P61271, RAB5A_MACFA;  Q9CQD1, RAB5A_MOUSE;  Q06AU6, RAB5A_PIG  ;
DR   M0RC99, RAB5A_RAT  ;  Q5ZHW4, RAB5B_CHICK;  P61020, RAB5B_HUMAN;
DR   P61021, RAB5B_MOUSE;  Q76NM7, RAB5B_PLAF7;  Q5RBG1, RAB5B_PONAB;
DR   Q58DS9, RAB5C_BOVIN;  P51147, RAB5C_CANLF;  Q98932, RAB5C_CHICK;
DR   P51148, RAB5C_HUMAN;  P35278, RAB5C_MOUSE;  Q5R7L7, RAB5C_PONAB;
DR   Q9V3I2, RAB5_DROME ;  A6QR46, RAB6B_BOVIN;  Q9NRW1, RAB6B_HUMAN;
DR   P61294, RAB6B_MOUSE;  Q3T0F5, RAB7A_BOVIN;  P18067, RAB7A_CANLF;
DR   P36411, RAB7A_DICDI;  P51149, RAB7A_HUMAN;  P51150, RAB7A_MOUSE;
DR   Q95UJ0, RAB7A_PAROT;  Q5R9Y4, RAB7A_PONAB;  O97572, RAB7A_RABIT;
DR   P09527, RAB7A_RAT  ;  O76742, RAB7_DROME ;  A4FV54, RAB8A_BOVIN;
DR   P61007, RAB8A_CANLF;  Q5F470, RAB8A_CHICK;  P61006, RAB8A_HUMAN;
DR   Q4R5P1, RAB8A_MACFA;  P55258, RAB8A_MOUSE;  Q5R4A3, RAB8A_PONAB;
DR   P35280, RAB8A_RAT  ;  P62998, RAC1_BOVIN ;  P62999, RAC1_CANLF ;
DR   P80236, RAC1_CAVPO ;  P63000, RAC1_HUMAN ;  P63001, RAC1_MOUSE ;
DR   Q6RUV5, RAC1_RAT   ;  P60763, RAC3_HUMAN ;  P60764, RAC3_MOUSE ;
DR   Q24814, RACA_ENTH1 ;  Q24815, RACB_ENTH1 ;  Q24816, RACC_ENTH1 ;
DR   Q24817, RACD_ENTH1 ;  O76321, RACG_ENTH1 ;  P48555, RALA_DROME ;
DR   P11233, RALA_HUMAN ;  P63321, RALA_MOUSE ;  P63322, RALA_RAT   ;
DR   P63320, RALA_SAGOE ;  Q9YH09, RALBA_XENLA;  Q6IP71, RALBB_XENLA;
DR   P11234, RALB_HUMAN ;  Q4R379, RALB_MACFA ;  Q9JIW9, RALB_MOUSE ;
DR   Q5R4B8, RALB_PONAB ;  P36860, RALB_RAT   ;  P22124, RAL_DIPOM  ;
DR   P62833, RAP1A_BOVIN;  P62834, RAP1A_HUMAN;  P62835, RAP1A_MOUSE;
DR   P62836, RAP1A_RAT  ;  P61223, RAP1B_BOVIN;  Q5ZHX1, RAP1B_CHICK;
DR   Q9YH37, RAP1B_CYPCA;  Q6TEN1, RAP1B_DANRE;  P61224, RAP1B_HUMAN;
DR   Q4R9D4, RAP1B_MACFA;  Q99JI6, RAP1B_MOUSE;  A5A6J7, RAP1B_PANTR;
DR   Q5RDM6, RAP1B_PONAB;  Q62636, RAP1B_RAT  ;  Q7ZXH7, RAP1B_XENLA;
DR   Q640R7, RAP1B_XENTR;  Q18246, RAP1_CAEEL ;  P08645, RAP1_DROME ;
DR   Q94694, RAP1_PHYPO ;  P10114, RAP2A_HUMAN;  Q80ZJ1, RAP2A_MOUSE;
DR   Q06AU2, RAP2A_PIG  ;  Q5R988, RAP2A_PONAB;  P61225, RAP2B_HUMAN;
DR   P61226, RAP2B_MOUSE;  P61227, RAP2B_RAT  ;  Q08DI5, RAP2C_BOVIN;
DR   Q9Y3L5, RAP2C_HUMAN;  Q8BU31, RAP2C_MOUSE;  P18613, RAPA_DICDI ;
DR   P22123, RAPA_DIPOM ;  Q86L51, RAPB_DICDI ;  Q55BW0, RAPC_DICDI ;
DR   C4YKT4, RAS1_CANAW ;  P0CY32, RAS1_CANAX ;  B3M185, RAS1_DROAN ;
DR   B3NZR4, RAS1_DROER ;  B4JFU8, RAS1_DROGR ;  P83832, RAS1_DROMA ;
DR   P08646, RAS1_DROME ;  B4KB60, RAS1_DROMO ;  B4GFJ8, RAS1_DROPE ;
DR   Q295X7, RAS1_DROPS ;  B4HKC7, RAS1_DROSE ;  P83831, RAS1_DROSI ;
DR   B4LY29, RAS1_DROVI ;  B4NJ72, RAS1_DROWI ;  B4PUP5, RAS1_DROYA ;
DR   P51539, RAS1_HYDVU ;  P22278, RAS1_MUCCL ;  P22126, RAS1_NEUCR ;
DR   P34729, RAS1_PHYPO ;  P01119, RAS1_YEAST ;  P04388, RAS2_DROME ;
DR   P38976, RAS2_HYDVU ;  P22279, RAS2_MUCCL ;  Q01387, RAS2_NEUCR ;
DR   P34726, RAS2_PHYPO ;  P01120, RAS2_YEAST ;  P22280, RAS3_MUCCL ;
DR   P32252, RASB_DICDI ;  P32253, RASC_DICDI ;  P03967, RASD_DICDI ;
DR   Q7Z444, RASE_HUMAN ;  Q7TN89, RASE_MOUSE ;  P15064, RASG_DICDI ;
DR   P08642, RASH_CHICK ;  P01112, RASH_HUMAN ;  Q60529, RASH_MESAU ;
DR   Q61411, RASH_MOUSE ;  P01115, RASH_MSVHA ;  P01113, RASH_MSVMO ;
DR   P23175, RASH_MSVNS ;  P20171, RASH_RAT   ;  P01114, RASH_RRASV ;
DR   Q9YH38, RASK_CYPCA ;  P01116, RASK_HUMAN ;  Q5EFX7, RASK_KRYMA ;
DR   P79800, RASK_MELGA ;  Q07983, RASK_MONDO ;  P32883, RASK_MOUSE ;
DR   P01117, RASK_MSVKI ;  O42277, RASK_ORYLA ;  P08644, RASK_RAT   ;
DR   Q05147, RASK_XENLA ;  Q08E00, RASLC_BOVIN;  Q7SZ59, RASLC_DANRE;
DR   Q9NYN1, RASLC_HUMAN;  Q08AT1, RASLC_MOUSE;  O42785, RASL_COLTR ;
DR   A8NU18, RASL_COPC7 ;  Q05058, RASL_COPCI ;  O14807, RASM_HUMAN ;
DR   O08989, RASM_MOUSE ;  P97538, RASM_RAT   ;  P12825, RASN_CAVPO ;
DR   Q5F352, RASN_CHICK ;  P79737, RASN_DANRE ;  P01111, RASN_HUMAN ;
DR   Q95ME4, RASN_MONDO ;  P08556, RASN_MOUSE ;  Q2MJK3, RASN_PIG   ;
DR   Q5RD87, RASN_PONAB ;  Q04970, RASN_RAT   ;  Q91806, RASN_XENLA ;
DR   P32254, RASS_DICDI ;  Q55CB0, RASU_DICDI ;  Q55CB9, RASV_DICDI ;
DR   Q55CC0, RASW_DICDI ;  Q55CB8, RASX_DICDI ;  Q55CB7, RASY_DICDI ;
DR   Q55CA9, RASZ_DICDI ;  P18262, RAS_ARTSA  ;  P87018, RAS_BOTFU  ;
DR   P05774, RAS_CARAU  ;  P0CQ43, RAS_CRYNB  ;  P0CQ42, RAS_CRYNJ  ;
DR   Q12526, RAS_EMENI  ;  P24498, RAS_GEOCY  ;  O93856, RAS_LACBI  ;
DR   P28775, RAS_LENED  ;  Q91079, RAS_LIMLI  ;  P08647, RAS_SCHPO  ;
DR   Q2TA29, RB11A_BOVIN;  P62490, RB11A_CANLF;  Q5ZJN2, RB11A_CHICK;
DR   P62491, RB11A_HUMAN;  P62492, RB11A_MOUSE;  Q52NJ1, RB11A_PIG  ;
DR   Q5R9M7, RB11A_PONAB;  P62493, RB11A_RABIT;  P62494, RB11A_RAT  ;
DR   Q3MHP2, RB11B_BOVIN;  Q15907, RB11B_HUMAN;  P46638, RB11B_MOUSE;
DR   O35509, RB11B_RAT  ;  Q1HE58, RB27A_CANLF;  P51159, RB27A_HUMAN;
DR   Q9ERI2, RB27A_MOUSE;  Q4LE85, RB27A_PIG  ;  P23640, RB27A_RAT  ;
DR   Q8HZJ5, RB27B_BOVIN;  O00194, RB27B_HUMAN;  Q99P58, RB27B_MOUSE;
DR   Q99P74, RB27B_RAT  ;  A6QP66, RERGL_BOVIN;  Q6DGN0, RERGL_DANRE;
DR   Q9H628, RERGL_HUMAN;  Q0VCJ7, RERG_BOVIN ;  Q96A58, RERG_HUMAN ;
DR   Q8R367, RERG_MOUSE ;  P31021, RHO1_ENTH1 ;  P06780, RHO1_YEAST ;
DR   P06781, RHO2_YEAST ;  Q00246, RHO4_YEAST ;  P61585, RHOA_BOVIN ;
DR   P24406, RHOA_CANLF ;  P61586, RHOA_HUMAN ;  Q9QUI0, RHOA_MOUSE ;
DR   Q5REY6, RHOA_PONAB ;  P61589, RHOA_RAT   ;  Q92963, RIT1_HUMAN ;
DR   P70426, RIT1_MOUSE ;  Q99578, RIT2_HUMAN ;  P70425, RIT2_MOUSE ;
DR   Q5BJQ5, RIT2_RAT   ;  A6NIZ1, RP1BL_HUMAN;  Q92737, RSLAA_HUMAN;
DR   Q8K5A4, RSLAA_MOUSE;  Q96S79, RSLAB_HUMAN;  Q5SSG5, RSLAB_MOUSE;
DR   Q6T310, RSLBA_HUMAN;  Q6IMB1, RSLBA_MOUSE;  Q6IMA3, RSLBA_RAT  ;
DR   Q5E9J3, RSLBB_BOVIN;  Q6P0U3, RSLBB_DANRE;  Q9BPW5, RSLBB_HUMAN;
DR   Q922H7, RSLBB_MOUSE;  Q6IMA7, RSLBB_RAT  ;  Q8AVS6, RSLBB_XENLA;
DR   Q5FVY2, RSLBB_XENTR;  A1DZY4, RSLBL_DANRE;  P52498, RSR1_CANAX ;
DR   P13856, RSR1_YEAST ;
//