Expasy logo

ENZYME

ENZYME entry: EC 3.7.1.17

Accepted Name
4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
Reaction catalysed
(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O = (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+)
Comment(s)
The enzyme is involved in the bacterial degradation of the steroid ring structure, and is involved in degradation of multiple steroids, such as testosterone, cholesterol, and sitosterol.
Cross-references
BRENDA3.7.1.17
EC2PDB3.7.1.17
ExplorEnz3.7.1.17
PRIAM enzyme-specific profiles3.7.1.17
KEGG Ligand Database for Enzyme Nomenclature3.7.1.17
IUBMB Enzyme Nomenclature3.7.1.17
IntEnz3.7.1.17
MEDLINEFind literature relating to 3.7.1.17
MetaCyc3.7.1.17
Rhea expert-curated reactions3.7.1.17
UniProtKB/Swiss-Prot
P9WNH4, HSAD_MYCTOP9WNH5, HSAD_MYCTUQ9KWQ6, HSAD_RHOJR

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-