ID 3.7.1.18 DE 6-oxocamphor hydrolase. CA bornane-2,6-dione + H2O = [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3- CA enyl]acetate + H(+). CC -!- Isolated from Rhodococcus sp. CC -!- The bornane ring system is cleaved by a retro-Claisen reaction to CC give the enol of alpha-campholonate. CC -!- When separate from the enzyme the enol is tautomerised to the keto CC form as a 6:1 mixture of [(1S,3R)-2,2,3-trimethyl-4- CC oxocyclopentyl]acetate and [(1S,3S)-2,2,3-trimethyl-4- CC oxocyclopentyl]acetate. DR Q93TU6, CAMK_RHOSO ; //