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ENZYME

ENZYME entry: EC 3.8.2.2

PURL: https://purl.expasy.org/enzyme/EC/3.8.2.2
Accepted Name
diisopropyl-fluorophosphatase
Alternative Name(s)
DFPase
diisopropylfluorophosphonate dehalogenase
diisopropylphosphofluoridase
isopropylphosphorofluoridase
OPAA
OPA anhydrase
organophosphate acid anhydrase
organophosphorus acid anhydrolase
somanase
tabunase
Reaction catalysed
diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)
Comment(s)
  • Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).
  • Inhibited by chelating agents; required divalent cations.
  • Related to EC 3.1.8.1.
  • Formerly EC 3.1.8.2.
Cross-references
Rhea expert-curated reactions3.8.2.2
ExplorEnz3.8.2.2
IUBMB Enzyme Nomenclature3.8.2.2
UniProtKB/Swiss-Prot
Q7SIG4, DFPA_LOLVUQ44238, PEPQ_ALTSXP77814, PEPQ_PSEHA
BRENDA3.8.2.2
MetaCyc3.8.2.2
KEGG Ligand Database for Enzyme Nomenclature3.8.2.2
EC2PDB3.8.2.2
MEDLINEFind literature relating to 3.8.2.2

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.8.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-