ID   4.1.2.43
DE   3-hexulose-6-phosphate synthase.
AN   3-hexulosephosphate synthase.
AN   3-hexulose phosphate synthase.
AN   D-arabino-3-hexulose 6-phosphate formaldehyde-lyase.
AN   HPS.
CA   D-ribulose 5-phosphate + formaldehyde = D-arabino-hex-3-ulose
CA   6-phosphate.
CC   -!- Specific for formaldehyde and D-ribulose 5-phosphate as substrates.
CC   -!- Ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and
CC       fructose 6-phosphate cannot act as substrate.
CC   -!- This enzyme, along with EC 5.3.1.27, plays a key role in the
CC       ribulose-monophosphate cycle of formaldehyde fixation, which is
CC       present in many microorganisms that are capable of utilizing
CC       C1-compounds.
CC   -!- The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii
CC       OT3 constitutively produces a bifunctional enzyme that sequentially
CC       catalyzes the reactions of this enzyme and EC 5.3.1.27.
DR   O28964, FAEHP_ARCFU;  Q8THA9, FAEHP_METAC;  Q0W644, FAEHP_METAR;
DR   A7I6C9, FAEHP_METB6;  Q46DY5, FAEHP_METBF;  Q12UK3, FAEHP_METBU;
DR   Q2FQ74, FAEHP_METHJ;  Q58842, FAEHP_METJA;  Q8PXE1, FAEHP_METMA;
DR   A3CUG8, FAEHP_METMJ;  B8GGX9, FAEHP_METPE;  Q2NE86, FAEHP_METST;
DR   O27518, FAEHP_METTH;  A0B7U9, FAEHP_METTP;  Q49WT7, HPS1_STAS1 ;
DR   Q49WT0, HPS2_STAS1 ;  Q49VB7, HPS3_STAS1 ;  P42405, HPS_BACSU  ;
DR   Q48907, HPS_METAM  ;  Q46DA4, HPS_METBF  ;  Q9LBW4, HPS_MYCGS  ;
DR   Q2FJ70, HPS_STAA3  ;  Q2G0K7, HPS_STAA8  ;  Q2YS94, HPS_STAAB  ;
DR   Q5HIA5, HPS_STAAC  ;  Q99W39, HPS_STAAM  ;  Q7A774, HPS_STAAN  ;
DR   Q6GJ99, HPS_STAAR  ;  Q6GBR7, HPS_STAAS  ;  Q8NXX1, HPS_STAAW  ;
DR   Q5HRH7, HPS_STAEQ  ;  Q8CQ69, HPS_STAES  ;  Q4L3P8, HPS_STAHJ  ;
//