ID   4.1.99.1
DE   tryptophanase.
AN   L-tryptophan indole-lyase.
AN   TNase.
CA   L-tryptophan + H2O = indole + pyruvate + NH4(+).
CC   -!- The enzyme cleaves a carbon-carbon bond, releasing indole and an
CC       unstable enamine product that tautomerizes to an imine form, which
CC       undergoes a hydrolytic deamination to form pyruvate and ammonia.
CC   -!- The latter reaction, which can occur spontaneously, can also be
CC       catalyzed by EC 3.5.99.10.
CC   -!- Also catalyzes 2,3-elimination and beta-replacement reactions of some
CC       indole-substituted tryptophan analogs of L-cysteine, L-serine and
CC       other 3-substituted amino acids.
DR   P31014, TNAA1_SYMTH;  P31015, TNAA2_SYMTH;  A0KJP3, TNAA_AERHH ;
DR   Q9YCI2, TNAA_AERPE ;  A4SNA7, TNAA_AERS4 ;  Q8R9K5, TNAA_CALS4 ;
DR   Q7NYV9, TNAA_CHRVO ;  A8AKE2, TNAA_CITK8 ;  Q894M8, TNAA_CLOTE ;
DR   A7ZTR3, TNAA_ECO24 ;  B7UMH5, TNAA_ECO27 ;  B7MGC9, TNAA_ECO45 ;
DR   B7L853, TNAA_ECO55 ;  Q8XB34, TNAA_ECO57 ;  B5YXB2, TNAA_ECO5E ;
DR   B7NR10, TNAA_ECO7I ;  B7N212, TNAA_ECO81 ;  B7M560, TNAA_ECO8A ;
DR   C4ZYY6, TNAA_ECOBW ;  B1X9T7, TNAA_ECODH ;  A8A6H0, TNAA_ECOHS ;
DR   Q0TB00, TNAA_ECOL5 ;  Q8FBV2, TNAA_ECOL6 ;  B1IX30, TNAA_ECOLC ;
DR   P0A853, TNAA_ECOLI ;  B7NF25, TNAA_ECOLU ;  B6I3U1, TNAA_ECOSE ;
DR   B1LL35, TNAA_ECOSM ;  B7LK50, TNAA_ESCF3 ;  Q4QML4, TNAA_HAEI8 ;
DR   O07674, TNAA_HAEIF ;  B0R7Q6, TNAA_HALS3 ;  Q9HMV2, TNAA_HALSA ;
DR   Q0I3R5, TNAA_HISS1 ;  B0UTZ3, TNAA_HISS2 ;  Q0C406, TNAA_HYPNA ;
DR   Q59342, TNAA_KLEAE ;  Q729Z3, TNAA_NITV2 ;  A1VC86, TNAA_NITV4 ;
DR   Q9CL27, TNAA_PASMU ;  Q7N8C9, TNAA_PHOLL ;  Q9ZNA8, TNAA_PROIN ;
DR   P28796, TNAA_PROVU ;  O30971, TNAA_RHOCA ;  Q2S1V4, TNAA_SALRD ;
DR   A8G097, TNAA_SHESH ;  B2TUR7, TNAA_SHIB3 ;  Q0SYP7, TNAA_SHIF8 ;
DR   P0A854, TNAA_SHIFL ;  A5EYI0, TNAA_VIBC3 ;  Q9KN05, TNAA_VIBCH ;
DR   C3LUI5, TNAA_VIBCM ;  Q87JQ6, TNAA_VIBPA ;  Q8D5Q4, TNAA_VIBVU ;
DR   Q7MCR1, TNAA_VIBVY ;  A1JJH3, TNAA_YERE8 ;
//