ID   4.1.99.22
DE   GTP 3',8-cyclase.
CA   AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-
CA   dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) +
CA   L-methionine.
CC   -!- The enzyme catalyzes an early step in the biosynthesis of the
CC       molybdenum cofactor (MoCo).
CC   -!- The enzyme belongs to the superfamily of radical S-adenosyl-L-
CC       methionine (radical SAM) enzymes.
CC   -!- Formerly EC 4.1.99.18.
DR   Q39055, CNX2_ARATH ;  Q7TX84, MOAA1_MYCBO;  P9WJS2, MOAA1_MYCTO;
DR   P9WJS3, MOAA1_MYCTU;  Q9HXD6, MOAA1_PSEAE;  P65385, MOAA2_MYCBO;
DR   P9WJS0, MOAA2_MYCTO;  P9WJS1, MOAA2_MYCTU;  Q9I3K7, MOAA2_PSEAE;
DR   P62588, MOAA3_MYCBO;  P62589, MOAA3_MYCTO;  B0CDZ6, MOAA_ACAM1 ;
DR   A0LVG0, MOAA_ACIC1 ;  A3N054, MOAA_ACTP2 ;  B3GXC5, MOAA_ACTP7 ;
DR   B0BNX2, MOAA_ACTPJ ;  A6VPY2, MOAA_ACTSZ ;  A0KIL8, MOAA_AERHH ;
DR   Q9YEV3, MOAA_AERPE ;  Q8UER0, MOAA_AGRFC ;  A8ERS0, MOAA_ALIB4 ;
DR   A6TVF9, MOAA_ALKMQ ;  A8MLW5, MOAA_ALKOO ;  O67929, MOAA_AQUAE ;
DR   O28273, MOAA_ARCFU ;  C3LA56, MOAA_BACAC ;  A7GU01, MOAA_BACCN ;
DR   Q65DY5, MOAA_BACLD ;  P39757, MOAA_BACSU ;  A7Z9P0, MOAA_BACVZ ;
DR   Q89NT2, MOAA_BRADU ;  C0Z9B3, MOAA_BREBN ;  B2S5I1, MOAA_BRUA1 ;
DR   Q2YNT7, MOAA_BRUA2 ;  Q57DG3, MOAA_BRUAB ;  A9MAX5, MOAA_BRUC2 ;
DR   C0RIT4, MOAA_BRUMB ;  Q8YGY6, MOAA_BRUME ;  A5VQC9, MOAA_BRUO2 ;
DR   B0CLT0, MOAA_BRUSI ;  Q8G0X4, MOAA_BRUSU ;  A7ZB87, MOAA_CAMC1 ;
DR   A7GWA5, MOAA_CAMC5 ;  A0RMJ2, MOAA_CAMFF ;  A8FJX0, MOAA_CAMJ8 ;
DR   A7H1N9, MOAA_CAMJD ;  Q9PIW6, MOAA_CAMJE ;  A1VXP5, MOAA_CAMJJ ;
DR   Q5HX04, MOAA_CAMJR ;  B9KDV3, MOAA_CAMLR ;  Q3ADX8, MOAA_CARHZ ;
DR   Q9AC48, MOAA_CAUVC ;  P59038, MOAA_CHLTE ;  Q97HL8, MOAA_CLOAB ;
DR   A7FUZ6, MOAA_CLOB1 ;  C3KXJ8, MOAA_CLOB6 ;  A5I365, MOAA_CLOBH ;
DR   C1FPG7, MOAA_CLOBJ ;  B1IN35, MOAA_CLOBK ;  A7GEQ5, MOAA_CLOBL ;
DR   B1KU20, MOAA_CLOBM ;  Q0TPG6, MOAA_CLOP1 ;  Q9WX96, MOAA_CLOPE ;
DR   Q0SS32, MOAA_CLOPS ;  A4QDF8, MOAA_CORGB ;  Q8NR60, MOAA_CORGL ;
DR   B1X0G3, MOAA_CROS5 ;  A7MJ10, MOAA_CROS8 ;  B8HWW4, MOAA_CYAP4 ;
DR   A4J6S5, MOAA_DESRM ;  A8LIR8, MOAA_DINSH ;  A7ZJJ0, MOAA_ECO24 ;
DR   B7ULX8, MOAA_ECO27 ;  B7MGN9, MOAA_ECO45 ;  B7LC63, MOAA_ECO55 ;
DR   P65383, MOAA_ECO57 ;  B5YRM0, MOAA_ECO5E ;  B7NNL1, MOAA_ECO7I ;
DR   B7MQN5, MOAA_ECO81 ;  B7M753, MOAA_ECO8A ;  C4ZXV3, MOAA_ECOBW ;
DR   B1X7B1, MOAA_ECODH ;  A7ZY37, MOAA_ECOHS ;  P65382, MOAA_ECOL6 ;
DR   P30745, MOAA_ECOLI ;  B7NA81, MOAA_ECOLU ;  B6I7T6, MOAA_ECOSE ;
DR   B1LM72, MOAA_ECOSM ;  C5B7H2, MOAA_EDWI9 ;  Q2NCE3, MOAA_ERYLH ;
DR   B7LJY1, MOAA_ESCF3 ;  Q747W9, MOAA_GEOSL ;  Q7NCF5, MOAA_GLOVI ;
DR   Q7VLN1, MOAA_HAEDU ;  Q4QJR9, MOAA_HAEI8 ;  A5UBK4, MOAA_HAEIE ;
DR   A5UFB4, MOAA_HAEIG ;  P45311, MOAA_HAEIN ;  Q9K9W9, MOAA_HALH5 ;
DR   B0R2L5, MOAA_HALS3 ;  Q9HST4, MOAA_HALSA ;  Q18G49, MOAA_HALWD ;
DR   B0TI16, MOAA_HELMI ;  B6JM01, MOAA_HELP2 ;  Q1CTA2, MOAA_HELPH ;
DR   Q9ZL75, MOAA_HELPJ ;  P56414, MOAA_HELPY ;  Q31JB9, MOAA_HYDCU ;
DR   B5XYW6, MOAA_KLEP3 ;  A6T6M5, MOAA_KLEP7 ;  Q88WY1, MOAA_LACPL ;
DR   B2GCN4, MOAA_LIMF3 ;  Q92CY2, MOAA_LISIN ;  C1L1W8, MOAA_LISMC ;
DR   Q721B9, MOAA_LISMF ;  Q8Y870, MOAA_LISMO ;  A0AHG0, MOAA_LISW6 ;
DR   A0L7R4, MOAA_MAGMM ;  Q65TT2, MOAA_MANSM ;  A1U578, MOAA_MARN8 ;
DR   C6C060, MOAA_MARSD ;  A6UX30, MOAA_META3 ;  Q8TUG2, MOAA_METAC ;
DR   Q0W3L5, MOAA_METAR ;  Q58234, MOAA_METJA ;  Q8TV60, MOAA_METKA ;
DR   A4FYQ8, MOAA_METM5 ;  A9A661, MOAA_METM6 ;  A6VJM2, MOAA_METM7 ;
DR   Q8PX29, MOAA_METMA ;  Q6LZQ3, MOAA_METMP ;  A4YH62, MOAA_METS5 ;
DR   O27593, MOAA_METTH ;  Q50746, MOAA_METTM ;  A6US67, MOAA_METVS ;
DR   B0JNC2, MOAA_MICAN ;  Q2RGL2, MOAA_MOOTA ;  B2HFA4, MOAA_MYCMM ;
DR   A0R443, MOAA_MYCS2 ;  A3Q648, MOAA_MYCSJ ;  A1ULP7, MOAA_MYCSK ;
DR   Q1B3F3, MOAA_MYCSS ;  A0PKZ7, MOAA_MYCUA ;  B9L851, MOAA_NAUPA ;
DR   Q1QN98, MOAA_NITHX ;  A6Q5D0, MOAA_NITSB ;  Q3STB0, MOAA_NITWN ;
DR   B2J1M7, MOAA_NOSP7 ;  Q8YQG6, MOAA_NOSS1 ;  Q44118, MOAA_PAENI ;
DR   A1B4A2, MOAA_PARDP ;  Q7U3H2, MOAA_PARMW ;  Q9CN21, MOAA_PASMU ;
DR   Q6D3C7, MOAA_PECAS ;  A5CYZ0, MOAA_PELTS ;  Q93KD1, MOAA_PEPAC ;
DR   A9BF51, MOAA_PETMO ;  Q7N6P6, MOAA_PHOLL ;  B1XLR4, MOAA_PICP2 ;
DR   Q48HV8, MOAA_PSE14 ;  Q1I6J5, MOAA_PSEE4 ;  A4XW05, MOAA_PSEMY ;
DR   A5VZZ2, MOAA_PSEP1 ;  Q3KAS8, MOAA_PSEPF ;  B0KST1, MOAA_PSEPG ;
DR   Q88E69, MOAA_PSEPK ;  B1JCW0, MOAA_PSEPW ;  Q882V6, MOAA_PSESM ;
DR   Q4ZU05, MOAA_PSEU2 ;  A1SWQ3, MOAA_PSYIN ;  Q9V2G2, MOAA_PYRAB ;
DR   Q8ZYE5, MOAA_PYRAE ;  Q8U4J5, MOAA_PYRFU ;  O57854, MOAA_PYRHO ;
DR   Q8Y0K4, MOAA_RALN1 ;  B3PQ08, MOAA_RHIE6 ;  Q2K7L4, MOAA_RHIEC ;
DR   Q98MK6, MOAA_RHILO ;  B5ZRM8, MOAA_RHILW ;  Q92PB4, MOAA_RHIME ;
DR   Q7UT69, MOAA_RHOBA ;  Q9X5W3, MOAA_RHOCA ;  Q0S2N2, MOAA_RHOJR ;
DR   C1B1N5, MOAA_RHOOB ;  Q3V7S1, MOAA_RHOPA ;  Q139F2, MOAA_RHOPS ;
DR   B3QCQ7, MOAA_RHOPT ;  B7JWW6, MOAA_RIPO1 ;  Q21I62, MOAA_SACD2 ;
DR   Q980F0, MOAA_SACS2 ;  B5F079, MOAA_SALA4 ;  B5FP68, MOAA_SALDC ;
DR   B5QX73, MOAA_SALEP ;  B5R769, MOAA_SALG2 ;  B4TC55, MOAA_SALHS ;
DR   B4SZK4, MOAA_SALNS ;  Q5PG37, MOAA_SALPA ;  A9MTH7, MOAA_SALPB ;
DR   C0PWZ0, MOAA_SALPC ;  B5BC24, MOAA_SALPK ;  B4TQU6, MOAA_SALSV ;
DR   P65387, MOAA_SALTI ;  P65386, MOAA_SALTY ;  Q12T28, MOAA_SHEDO ;
DR   B2TVE9, MOAA_SHIB3 ;  Q324B1, MOAA_SHIBS ;  Q32I50, MOAA_SHIDS ;
DR   Q83S40, MOAA_SHIFL ;  Q3Z403, MOAA_SHISS ;  A6U9U3, MOAA_SINMW ;
DR   A7X5J1, MOAA_STAA1 ;  A6U3Z2, MOAA_STAA2 ;  Q2FEM4, MOAA_STAA3 ;
DR   P69848, MOAA_STAA8 ;  A5IV50, MOAA_STAA9 ;  Q2YYS8, MOAA_STAAB ;
DR   Q5HDT9, MOAA_STAAC ;  A6QJA8, MOAA_STAAE ;  Q931G4, MOAA_STAAM ;
DR   P65388, MOAA_STAAN ;  Q6GEG6, MOAA_STAAR ;  Q6G754, MOAA_STAAS ;
DR   A8Z366, MOAA_STAAT ;  P65389, MOAA_STAAW ;  Q9ZIM6, MOAA_STACT ;
DR   Q5HLY1, MOAA_STAEQ ;  Q8CNE6, MOAA_STAES ;  Q4L8D2, MOAA_STAHJ ;
DR   Q49ZI6, MOAA_STAS1 ;  Q9RJ47, MOAA_STRCO ;  B4SL67, MOAA_STRM5 ;
DR   B2FUM0, MOAA_STRMK ;  Q4J8T0, MOAA_SULAC ;  Q30P92, MOAA_SULDN ;
DR   C3MZ99, MOAA_SULIA ;  C4KIH7, MOAA_SULIK ;  C3MR64, MOAA_SULIL ;
DR   C3MXF3, MOAA_SULIM ;  C3NGB5, MOAA_SULIN ;  C3N7B9, MOAA_SULIY ;
DR   A6Q6R2, MOAA_SULNB ;  Q971H1, MOAA_SULTO ;  Q56211, MOAA_SYNE7 ;
DR   Q2JI46, MOAA_SYNJB ;  Q5N5F7, MOAA_SYNP6 ;  Q9EYN8, MOAA_SYNPW ;
DR   Q3AVP9, MOAA_SYNS9 ;  Q3AGB7, MOAA_SYNSC ;  Q0AVU6, MOAA_SYNWW ;
DR   Q55369, MOAA_SYNY3 ;  Q9HKZ7, MOAA_THEAC ;  Q5JHN5, MOAA_THEKO ;
DR   Q979T0, MOAA_THEVO ;  B5YJ09, MOAA_THEYD ;  C4LFK3, MOAA_TOLAT ;
DR   Q119N9, MOAA_TRIEI ;  Q3MC34, MOAA_TRIV2 ;  B7VLU4, MOAA_VIBA3 ;
DR   A5F2Q5, MOAA_VIBC3 ;  Q9KT81, MOAA_VIBCH ;  C3LTS1, MOAA_VIBCM ;
DR   Q87MY0, MOAA_VIBPA ;  Q8D894, MOAA_VIBVU ;  Q7MM75, MOAA_VIBVY ;
DR   Q8PNH1, MOAA_XANAC ;  Q4URN0, MOAA_XANC8 ;  B0RTE0, MOAA_XANCB ;
DR   Q8PBX1, MOAA_XANCP ;  Q8ZGW5, MOAA_YERPE ;  Q1JQD7, MOCS1_BOVIN;
DR   Q20624, MOCS1_CAEEL;  Q54NM6, MOCS1_DICDI;  Q8IQF1, MOCS1_DROME;
DR   Q9NZB8, MOCS1_HUMAN;  Q5RKZ7, MOCS1_MOUSE;
//