ID   4.1.99.26
DE   3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
DE   synthase.
CA   [mycofactocin precursor peptide]-C-terminal glycyl-N-
CA   {[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-
CA   methionine = 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-
CA   terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-
CA   oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine.
CC   -!- This is a bifunctional radical AdoMet (radical SAM) enzyme that
CC       catalyzes the first two steps in the biosynthesis of the enzyme
CC       cofactor mycofactocin.
CC   -!- Activity requires the presence of the MftB chaperone.
CC   -!- The reaction occurs in the right-to-left direction.
CC   -!- The other activity of the enzyme is EC 1.3.98.7.
DR   A0QSB8, MFTC_MYCS2 ;  P9WJ78, MFTC_MYCTO ;  P9WJ79, MFTC_MYCTU ;
DR   A0PM49, MFTC_MYCUA ;
//