ID   4.2.1.117
DE   2-methylcitrate dehydratase (2-methyl-trans-aconitate forming).
CA   (2S,3S)-2-methylcitrate = 2-methyl-trans-aconitate + H2O.
CC   -!- Catalyzes the dehydration of (2S,3S)-2-methylcitrate, forming the
CC       trans isomer of 2-methyl-aconitate (unlike EC 4.2.1.79, which forms
CC       only the cis isomer).
CC   -!- Part of a propanoate degradation pathway.
CC   -!- The enzyme from Shewanella oneidensis can also accept citrate and
CC       cis-aconitate, but activity with (2S,3S)-2-methylcitrate was
CC       approximately 2.5-fold higher.
CC   -!- 2-methylisocitrate and isocitrate were not substrates.
DR   Q8EJW3, ACND_SHEON ;
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