ID   4.2.1.170
DE   2-(omega-methylthio)alkylmalate dehydratase.
CA   (1) a 2-(omega-methylsulfanyl)alkylmalate = a 2-(omega-
CA   methylsulfanyl)alkylmaleate + H2O.
CA   (2) a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-
CA   methylsulfanyl)alkylmaleate + H2O.
CC   -!- The enzyme, characterized from the plant Arabidopsis thaliana,
CC       is involved in the L-methionine side-chain elongation pathway,
CC       forming substrates for the biosynthesis of aliphatic glucosinolates.
CC   -!- By catalyzing a dehydration of a 2-(omega-
CC       methylsulfanyl)alkylmaleate, followed by a hydration at a different
CC       position, the enzyme achieves the isomerization of its substrates.
CC   -!- The enzyme is a heterodimer comprising a large and a small subunits.
CC   -!- The large subunit can also bind to an alternative small subunit,
CC       forming EC 4.2.1.33, which participates in L-leucine biosynthesis.
DR   Q94AR8, LEUC_ARATH ;  Q9ZW84, LEUD1_ARATH;  Q9LYT7, LEUD2_ARATH;
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