ID   4.2.1.36
DE   homoaconitate hydratase.
AN   2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase.
AN   cis-homoaconitase.
AN   HACN.
AN   homoaconitase.
CA   (2R,3S)-homoisocitrate = cis-homoaconitate + H2O.
CC   -!- The enzyme from the hyperthermophilic eubacterium Thermus
CC       thermophilus can catalyze the reaction shown above but cannot
CC       catalyze the previously described reaction, i.e. formation of
CC       homocitrate by hydration of cis-homoaconitate.
CC   -!- The enzyme responsible for the conversion of cis-homoaconitate into
CC       homocitrate in T.thermophilus is unknown at present but the reaction
CC       can be catalyzed in vitro using EC 4.2.1.3 from pig.
DR   Q9ZNE0, HACA_THET2 ;  Q9ZND9, HACB_THET2 ;  Q4WUL6, LYS4_ASPFU ;
DR   Q58FL6, LYS4_ASPNC ;  Q2U9G3, LYS4_ASPOR ;  Q5A644, LYS4_CANAL ;
DR   Q6FM51, LYS4_CANGA ;  Q2HZ33, LYS4_CANPA ;  Q2GN26, LYS4_CHAGB ;
DR   P0CM03, LYS4_CRYNB ;  P0CM02, LYS4_CRYNJ ;  Q6BM98, LYS4_DEBHA ;
DR   Q92412, LYS4_EMENI ;  Q75DX9, LYS4_EREGS ;  Q4HVQ9, LYS4_GIBZE ;
DR   Q6CT61, LYS4_KLULA ;  Q870W1, LYS4_NEUCR ;  Q9UT74, LYS4_SCHPO ;
DR   Q4P521, LYS4_USTMA ;  Q6C791, LYS4_YARLI ;  P49367, LYS4_YEAST ;
//