ID 4.2.1.78 DE (S)-norcoclaurine synthase. AN (S)-norlaudanosoline synthase. CA (4-hydroxyphenyl)acetaldehyde + dopamine = (S)-norcoclaurine + H2O. CC -!- The reaction makes a 6-membered ring by forming a bond between C-6 of CC the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde CC in the imine formed between the substrates. CC -!- The product is the precursor of the benzylisoquinoline alkaloids in CC plants. CC -!- Will also catalyze the reaction of 4-(2-aminoethyl)benzene-1,2-diol + CC (3,4-dihydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline, CC but this alkaloid has not been found to occur in plants. DR A2A1A0, NCS1_COPJA ; Q4QTJ2, NCS1_PAPSO ; A2A1A1, NCS2_COPJA ; DR Q4QTJ1, NCS2_PAPSO ; Q67A25, NCS_THLFG ; //