ID 4.2.2.21 DE chondroitin-sulfate-ABC exolyase. AN chondroitin ABC eliminase. AN chondroitin ABC lyase. AN chondroitinase. AN chondroitinase ABC. AN chondroitin sulfate ABC exoeliminase. AN chondroitin sulfate ABC exolyase. AN chondroitin sulfate ABC lyase. AN ChS ABC lyase. AN ChS ABC lyase II. CA Exolytic removal of Delta(4)-unsaturated disaccharide residues from the CA non-reducing ends of both polymeric chondroitin/dermatan sulfates and CA their oligosaccharide fragments. CC -!- Degrades a variety of glycosaminoglycans of the chondroitin-sulfate- CC and dermatan-sulfate type. CC -!- Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan CC sulfate are the best substrates but the enzyme can also act on CC hyaluronan at a much lower rate. CC -!- The related enzyme EC 4.2.2.20 has the same substrate specificity but CC produces a mixture of oligosaccharides of different sizes that are CC ultimately degraded to tetra- and disaccharides. CC -!- Both enzymes act by the removal of a relatively acidic C-5 proton of CC the uronic acid followed by the elimination of a 4-linked hexosamine, CC resulting in the formation of an unsaturated C4-C5 bond on the CC hexuronic acid moiety of the products. CC -!- Formerly EC 4.2.2.4 and EC 4.2.99.6. DR C5G6D7, CABC2_BACT4; Q8A2I1, CABC2_BACTN; C7S340, CABC2_PROVU; //