ID   4.2.3.119
DE   (-)-alpha-pinene synthase.
AN   (-)-alpha-pinene/(-)-camphene synthase.
AN   (-)-alpha-pinene cyclase.
CA   (2E)-geranyl diphosphate = (1S,5S)-alpha-pinene + diphosphate.
CC   -!- Cyclase II of Salvia officinalis (sage) gives about equal parts (-)-
CC       alpha-pinene, (-)-beta-pinene and (-)-camphene, plus traces of other
CC       monoterpenoids.
CC   -!- (3S)-linalyl diphosphate can also be used by the enzyme in preference
CC       to (3R)-linalyl diphosphate.
CC   -!- The 4-pro-S hydrogen of geranyl diphosphate is lost.
CC   -!- The enzyme from Abies grandis (grand fir) gives roughly equal parts
CC       (-)-alpha-pinene and (-)-beta-pinene.
CC   -!- However the clone ag11 gave 35% (-)-limonene, 24% (-)-alpha-pinene
CC       and 20% (-)-beta-phellandrene.
CC   -!- Synthase I from Pinus taeda (loblolly pine) produces (-)-alpha-pinene
CC       with traces of (-)-beta-pinene.
CC   -!- The enzyme from Picea sitchensis (Sika spruce) forms 70% (-)-alpha-
CC       pinene and 30% (-)-beta-pinene.
CC   -!- The recombinant PmeTPS1 enzyme from Pseudotsuga menziesii (Douglas
CC       fir) gave roughly equal proportions of (-)-alpha-pinene and (-)-
CC       camphene plus traces of other monoterpenoids.
CC   -!- See also EC 4.2.3.120, EC 4.2.3.117, EC 4.2.3.16 and EC 4.2.3.52.
CC   -!- Formerly EC 4.1.99.8, EC 4.2.3.14 and EC 4.2.3.n7.
DR   R9QMY8, CAMPS_PINCO;  F2XF95, PINS1_PICGL;  F2XFA8, PINS1_PICSI;
DR   F2XF96, PINS2_PICGL;  Q6XDB5, PINS2_PICSI;  O23945, PINS_FRAVE ;
DR   Q84KL6, PT1_PINTA  ;  R9QMY9, SAPN1_PINBN;  R9QMR3, SAPN1_PINCO;
DR   R9QMR0, SBPN1_PINBN;  R9QMQ9, SBPN1_PINCO;  R9QMW5, SBPN2_PINBN;
DR   R9QMW1, SPIN1_PINBN;  O24475, TPSD3_ABIGR;  Q9M7C9, TPSDB_ABIGR;
//