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ENZYME entry: EC 4.2.3.141

Accepted Name
sclareol synthase.
Reaction catalysed
8-hydroxycopalyl diphosphate + H2O <=> diphosphate + sclareol
Comment(s)
  • Isolated from the plant Salvia sclarea (clary sage).
  • Originally thought to be synthesized in one step from geranylgeranyl diphosphate it is now known to require two enzymes, EC 4.2.1.133 and EC 4.2.3.141.
  • Sclareol is used in perfumery.
  • Formerly EC 3.1.7.4.
Cross-references
BRENDA4.2.3.141
EC2PDB4.2.3.141
ExplorEnz4.2.3.141
PRIAM enzyme-specific profiles4.2.3.141
KEGG Ligand Database for Enzyme Nomenclature4.2.3.141
IUBMB Enzyme Nomenclature4.2.3.141
IntEnz4.2.3.141
MEDLINEFind literature relating to 4.2.3.141
MetaCyc4.2.3.141
Rhea expert-curated reactions4.2.3.141
UniProtKB/Swiss-Prot
G8GJ94, SCLS_SALSC

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-