ID 4.2.3.156 DE hydroxysqualene synthase. CA H2O + presqualene diphosphate = diphosphate + hydroxysqualene. CC -!- This enzyme, isolated from the bacteria Rhodopseudomonas palustris CC and Zymomonas mobilis, participates, along with EC 2.5.1.103 and CC EC 1.17.18.1, in the conversion of all-trans-farnesyl diphosphate to CC squalene. CC -!- Eukaryotes achieve the same goal in a single step, catalyzed by CC EC 2.5.1.21. DR Q6N3F1, HPNC_RHOPA ; P55351, HPNC_SINFN ; Q5NP67, HPNC_ZYMMO ; //