ID 4.2.3.201 DE hydropyrene synthase. CA (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + hydropyrene. CC -!- Isolated from the bacterium Streptomyces clavuligerus. CC -!- The 1-proR hydrogen atom of geranylgeranyl diphosphate is lost in the CC reaction. CC -!- The enzyme also produces hydropyrenol, isoelisabethatriene and traces CC of other diterpenoids. cf. EC 4.2.3.202 and EC 4.2.3.203. //